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Specific tolerance induction across a xenogeneic barrier: production of mixed rat/mouse lymphohematopoietic chimeras using a nonlethal preparative regimen.

Y Sharabi, I Aksentijevich, T M Sundt, 3rd, D H Sachs, M Sykes

J Exp Med (1990) 172 (1): 195–202.

https://doi.org/10.1084/jem.172.1.195

Published: 01 July 1990

View article titled, Specific tolerance induction across a xenogeneic barrier: production of mixed rat/mouse lymphohematopoietic chimeras using a nonlethal preparative regimen.

Journal Articles

In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment.

M Sykes, M L Romick, K A Hoyles, D H Sachs

J Exp Med (1990) 171 (3): 645–658.

https://doi.org/10.1084/jem.171.3.645

Published: 01 March 1990

View article titled, In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment.

Journal Articles

In vivo effects of monoclonal antibodies to distinct epitopes of Qa-2 antigens.

Y Sharabi, D H Sachs

J Exp Med (1990) 171 (1): 211–219.

https://doi.org/10.1084/jem.171.1.211

Published: 01 January 1990

View article titled, In vivo effects of monoclonal antibodies to distinct epitopes of Qa-2 antigens.

Journal Articles

Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen.

Y Sharabi, D H Sachs

J Exp Med (1989) 169 (2): 493–502.

https://doi.org/10.1084/jem.169.2.493

Published: 01 February 1989

View article titled, Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen.

Journal Articles

Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells.

M Sykes, M A Sheard, D H Sachs

J Exp Med (1988) 168 (6): 2391–2396.

https://doi.org/10.1084/jem.168.6.2391

Published: 01 December 1988

View article titled, Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells.

Journal Articles

Effects of T cell depletion in radiation bone marrow chimeras. II. Requirement for allogeneic T cells in the reconstituting bone marrow inoculum for subsequent resistance to breaking of tolerance.

M Sykes, M A Sheard, D H Sachs

J Exp Med (1988) 168 (2): 661–673.

https://doi.org/10.1084/jem.168.2.661

Published: 01 August 1988

View article titled, Effects of T cell depletion in radiation bone marrow chimeras. II. Requirement for allogeneic T cells in the reconstituting bone marrow inoculum for subsequent resistance to breaking of tolerance.

Journal Articles

The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones.

A Finnegan, M A Smith, J A Smith, J Berzofsky, D H Sachs, R J Hodes

J Exp Med (1986) 164 (3): 897–910.

https://doi.org/10.1084/jem.164.3.897

Published: 01 September 1986

View article titled, The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones.

Journal Articles

Alloresistance to engraftment of allogeneic donor bone marrow is mediated by an Lyt-2+ T cell in mixed allogeneic reconstitution (C57BL/10Sn + B10.D2/nSn----C57BL/10Sn).

S T Ildstad, J A Bluestone, D H Sachs

J Exp Med (1986) 163 (5): 1343–1348.

https://doi.org/10.1084/jem.163.5.1343

Published: 01 May 1986

View article titled, Alloresistance to engraftment of allogeneic donor bone marrow is mediated by an Lyt-2+ T cell in mixed allogeneic reconstitution (C57BL/10Sn + B10.D2/nSn----C57BL/10Sn).

Journal Articles

Cloned cytotoxic T lymphocytes that recognize an I-A region product in the context of a class I antigen.

N Shinohara, J A Bluestone, D H Sachs

J Exp Med (1986) 163 (4): 972–980.

https://doi.org/10.1084/jem.163.4.972

Published: 01 April 1986

View article titled, Cloned cytotoxic T lymphocytes that recognize an I-A region product in the context of a class I antigen.

Journal Articles

Evidence for a regulatory idiotypic network in the in vivo response to H-2 antigens.

R Rabinowitz, J A Bluestone, D H Sachs

J Exp Med (1985) 162 (2): 745–755.

https://doi.org/10.1084/jem.162.2.745

Published: 01 August 1985

View article titled, Evidence for a regulatory idiotypic network in the in vivo response to H-2 antigens.

Journal Articles

Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance.

S T Ildstad, S M Wren, J A Bluestone, S A Barbieri, D H Sachs

J Exp Med (1985) 162 (1): 231–244.

https://doi.org/10.1084/jem.162.1.231

Published: 01 July 1985

View article titled, Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance.

Journal Articles

Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens.

I Stroynowski, J Forman, R S Goodenow, S G Schiffer, M McMillan, S O Sharrow, D H Sachs, L Hood

J Exp Med (1985) 161 (5): 935–952.

https://doi.org/10.1084/jem.161.5.935

Published: 01 May 1985

View article titled, Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens.

Journal Articles

In vivo and in vitro characterization of specific hyporeactivity to skin xenografts in mixed xenogeneically reconstituted mice (B10 + F344 rat----B10).

S T Ildstad, S M Wren, S O Sharrow, D Stephany, D H Sachs

J Exp Med (1984) 160 (6): 1820–1835.

https://doi.org/10.1084/jem.160.6.1820

Published: 01 December 1984

View article titled, In vivo and in vitro characterization of specific hyporeactivity to skin xenografts in mixed xenogeneically reconstituted mice (B10 + F344 rat----B10).

Journal Articles

Effect of class II antigen matching on renal allograft survival in miniature swine.

M D Pescovitz, J R Thistlethwaite, Jr, H Auchincloss, Jr, S T Ildstad, T G Sharp, R Terrill, D H Sachs

J Exp Med (1984) 160 (5): 1495–1508.

https://doi.org/10.1084/jem.160.5.1495

Published: 01 November 1984

View article titled, Effect of class II antigen matching on renal allograft survival in miniature swine.

Journal Articles

Serologic cross-reactivity between Class I MHC molecules and an H-2-linked differentiation antigen as detected by monoclonal antibodies.

S O Sharrow, L Flaherty, D H Sachs

J Exp Med (1984) 159 (1): 21–40.

https://doi.org/10.1084/jem.159.1.21

Published: 01 January 1984

View article titled, Serologic cross-reactivity between Class I MHC molecules and an H-2-linked differentiation antigen as detected by monoclonal antibodies.

Journal Articles

Antiidiotypes against anti-H-2 monoclonal antibodies. V. In vivo antiidiotype treatment induces idiotype-specific helper T cells.

H Auchincloss, Jr, J A Bluestone, D H Sachs

J Exp Med (1983) 157 (4): 1273–1286.

https://doi.org/10.1084/jem.157.4.1273

Published: 01 April 1983

View article titled, Antiidiotypes against anti-H-2 monoclonal antibodies. V. In vivo antiidiotype treatment induces idiotype-specific helper T cells.

Journal Articles

Modification of T cell antinuclease idiotype expression by in vivo administration of anti-idiotype.

G G Miller, P I Nadler, R J Hodes, D H Sachs

J Exp Med (1982) 155 (1): 190–200.

https://doi.org/10.1084/jem.155.1.190

Published: 01 January 1982

View article titled, Modification of T cell antinuclease idiotype expression by in vivo administration of anti-idiotype.

Journal Articles

Protection against graft vs. host-associated immunosuppression in F1 mice. I. Activation of F1 regulatory cells by host-specific anti-major histocompatibility complex antibodies.

U Hurtenbach, D H Sachs, G M Shearer

J Exp Med (1981) 154 (6): 1922–1934.

https://doi.org/10.1084/jem.154.6.1922

Published: 01 December 1981

View article titled, Protection against graft vs. host-associated immunosuppression in F1 mice. I. Activation of F1 regulatory cells by host-specific anti-major histocompatibility complex antibodies.

Journal Articles

Anti-idiotypes to monoclonal anti-H-2 antibodies. II. Expression of anti-H-2Kk idiotypes on antibodies induced by anti-idiotype or H-2Kk antigen.

J A Bluestone, S L Epstein, K Ozato, S O Sharrow, D H Sachs

J Exp Med (1981) 154 (5): 1305–1318.

https://doi.org/10.1084/jem.154.5.1305

Published: 01 November 1981

View article titled, Anti-idiotypes to monoclonal anti-H-2 antibodies. II. Expression of anti-H-2Kk idiotypes on antibodies induced by anti-idiotype or H-2Kk antigen.

Journal Articles

Idiotypes of anti-Ia antibodies. I. Expression of the 14-4-4S idiotype in humoral immune responses.

S L Epstein, K Ozato, J A Bluestone, D H Sachs

J Exp Med (1981) 154 (2): 397–409.

https://doi.org/10.1084/jem.154.2.397

Published: 01 August 1981

View article titled, Idiotypes of anti-Ia antibodies. I. Expression of the 14-4-4S idiotype in humoral immune responses.

NARROW

Specific tolerance induction across a xenogeneic barrier: production of mixed rat/mouse lymphohematopoietic chimeras using a nonlethal preparative regimen.

In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment.

In vivo effects of monoclonal antibodies to distinct epitopes of Qa-2 antigens.

Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimen.

Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells.

Effects of T cell depletion in radiation bone marrow chimeras. II. Requirement for allogeneic T cells in the reconstituting bone marrow inoculum for subsequent resistance to breaking of tolerance.

The T cell repertoire for recognition of a phylogenetically distant protein antigen. Peptide specificity and MHC restriction of staphylococcal nuclease-specific T cell clones.

Alloresistance to engraftment of allogeneic donor bone marrow is mediated by an Lyt-2+ T cell in mixed allogeneic reconstitution (C57BL/10Sn + B10.D2/nSn----C57BL/10Sn).

Cloned cytotoxic T lymphocytes that recognize an I-A region product in the context of a class I antigen.

Evidence for a regulatory idiotypic network in the in vivo response to H-2 antigens.

Characterization of mixed allogeneic chimeras. Immunocompetence, in vitro reactivity, and genetic specificity of tolerance.

Expression and T cell recognition of hybrid antigens with amino-terminal domains encoded by Qa-2 region of major histocompatibility complex and carboxyl termini of transplantation antigens.

In vivo and in vitro characterization of specific hyporeactivity to skin xenografts in mixed xenogeneically reconstituted mice (B10 + F344 rat----B10).

Effect of class II antigen matching on renal allograft survival in miniature swine.

Serologic cross-reactivity between Class I MHC molecules and an H-2-linked differentiation antigen as detected by monoclonal antibodies.

Antiidiotypes against anti-H-2 monoclonal antibodies. V. In vivo antiidiotype treatment induces idiotype-specific helper T cells.

Modification of T cell antinuclease idiotype expression by in vivo administration of anti-idiotype.

Protection against graft vs. host-associated immunosuppression in F1 mice. I. Activation of F1 regulatory cells by host-specific anti-major histocompatibility complex antibodies.

Anti-idiotypes to monoclonal anti-H-2 antibodies. II. Expression of anti-H-2Kk idiotypes on antibodies induced by anti-idiotype or H-2Kk antigen.

Idiotypes of anti-Ia antibodies. I. Expression of the 14-4-4S idiotype in humoral immune responses.

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