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Volume 203, Issue 3

20 March 2006

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Table of Contents

ISSN 0022-1007

EISSN 1540-9538

In this Issue

In This Issue
From the Archive
Commentary
Brief Definitive Report
Article

In This Issue

Clot control

Heather L. Van Epps

View Articletitled, Clot control

Unhurried NK cells

Heather L. Van Epps

View Articletitled, Unhurried NK cells

Lulling septic shock to sleep

Heather L. Van Epps

View Articletitled, Lulling septic shock to sleep

Dying of excitement

Heather L. Van Epps

View Articletitled, Dying of excitement

Dividing with IL-7

Heather L. Van Epps

View Articletitled, Dividing with IL-7

T reg cells get specific

Heather L. Van Epps

View Articletitled, T reg cells get specific

From the Archive

Lymphocytes: not useless after all

Julie Clayton

View Articletitled, Lymphocytes: not useless after all

Commentary

In vivo sites and cellular mechanisms of T reg cell–mediated suppression

Alexander Y. Rudensky,Daniel J. Campbell

View Articletitled, In vivo sites and cellular mechanisms of T reg cell–mediated suppression

Are hemostasis and thrombosis two sides of the same coin?

Robert W. Colman

View Articletitled, Are hemostasis and thrombosis two sides of the same coin?

Mesenteric lymph nodes at the center of immune anatomy

Andrew J. Macpherson,Karen Smith

View Articletitled, Mesenteric lymph nodes at the center of immune anatomy

Immune responses and HIV: a little order from the chaos

David H. O'Connor,Dennis R. Burton

View Articletitled, Immune responses and HIV: a little order from the chaos

Brief Definitive Report

Regulatory T cells inhibit stable contacts between CD4⁺ T cells and dendritic cells in vivo

Carlos E. Tadokoro,Guy Shakhar,Shiqian Shen,Yi Ding,Andreia C. Lino,Antonio Maraver,Juan J. Lafaille,Michael L. Dustin

View Articletitled, Regulatory T cells inhibit stable contacts between CD4+ T cells and dendritic cells in vivo

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

Christoph Kleinschnitz,Guido Stoll,Martin Bendszus,Kai Schuh,Hans-Ulrich Pauer,Peter Burfeind,Christoph Renné,David Gailani,Bernhard Nieswandt,Thomas Renné

View Articletitled, Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

Article

Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

Tim Worbs,Ulrike Bode,Sheng Yan,Matthias W. Hoffmann,Gabriele Hintzen,Günter Bernhardt,Reinhold Förster,Oliver Pabst

View Articletitled, Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells

Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus

Rika Draenert,Todd M. Allen,Yang Liu,Terri Wrin,Colombe Chappey,Cori L. Verrill,Guillem Sirera,Robert L. Eldridge,Matthew P. Lahaie,Lidia Ruiz,Bonaventura Clotet,Christos J. Petropoulos,Bruce D. Walker,Javier Martinez-Picado

View Articletitled, Constraints on HIV-1 evolution and immunodominance revealed in monozygotic adult twins infected with the same virus

The primary defect in experimental ileitis originates from a nonhematopoietic source

Timothy S. Olson,Brian K. Reuter,Kevin G-E. Scott,Margaret A. Morris,Xiao-Ming Wang,Leslie N. Hancock,Tracy L. Burcin,Steven M. Cohn,Peter B. Ernst,Fabio Cominelli,Jonathan B. Meddings,Klaus Ley,Theresa T. Pizarro

View Articletitled, The primary defect in experimental ileitis originates from a nonhematopoietic source

TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE

Marc Ehlers,Hidehiro Fukuyama,Tracy L. McGaha,Alan Aderem,Jeffrey V. Ravetch

View Articletitled, TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE

Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia

Elena Gonzalez-Rey,Alejo Chorny,Gema Robledo,Mario Delgado

View Articletitled, Cortistatin, a new antiinflammatory peptide with therapeutic effect on lethal endotoxemia

IL-7 promotes T cell proliferation through destabilization of p27^Kip1

Wen Qing Li,Qiong Jiang,Eiman Aleem,Philipp Kaldis,Annette R. Khaled,Scott K. Durum

View Articletitled, IL-7 promotes T cell proliferation through destabilization of p27Kip1

Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery

Frank Tacke,Florent Ginhoux,Claudia Jakubzick,Nico van Rooijen,Miriam Merad,Gwendalyn J. Randolph

View Articletitled, Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery

Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses

Silvia B. Boscardin,Julius C.R. Hafalla,Revati F. Masilamani,Alice O. Kamphorst,Henry A. Zebroski,Urvashi Rai,Alexandre Morrot,Fidel Zavala,Ralph M. Steinman,Ruth S. Nussenzweig,Michel C. Nussenzweig

View Articletitled, Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses

Intensified and protective CD4⁺ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine

Christine Trumpfheller,Jennifer S. Finke,Carolina B. López,Thomas M. Moran,Bruno Moltedo,Helena Soares,Yaoxing Huang,Sarah J. Schlesinger,Chae Gyu Park,Michel C. Nussenzweig,Angela Granelli-Piperno,Ralph M. Steinman

View Articletitled, Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine

Natural killer cell behavior in lymph nodes revealed by static and real-time imaging

Marc Bajénoff,Béatrice Breart,Alex Y.C. Huang,Hai Qi,Julie Cazareth,Veronique M. Braud,Ronald N. Germain,Nicolas Glaichenhaus

View Articletitled, Natural killer cell behavior in lymph nodes revealed by static and real-time imaging

Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function

Makoto Yawata,Nobuyo Yawata,Monia Draghi,Ann-Margaret Little,Fotini Partheniou,Peter Parham

View Articletitled, Roles for HLA and KIR polymorphisms in natural killer cell repertoire selection and modulation of effector function

In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

Jingbo Yan,Vrajesh V. Parekh,Yanice Mendez-Fernandez,Danyvid Olivares-Villagómez,Srdjan Dragovic,Timothy Hill,Derry C. Roopenian,Sebastian Joyce,Luc Van Kaer

View Articletitled, In vivo role of ER-associated peptidase activity in tailoring peptides for presentation by MHC class Ia and class Ib molecules

A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

Lars Kjer-Nielsen,Natalie A. Borg,Daniel G. Pellicci,Travis Beddoe,Lyudmila Kostenko,Craig S. Clements,Nicholas A. Williamson,Mark J. Smyth,Gurdyal S. Besra,Hugh H. Reid,Mandvi Bharadwaj,Dale I. Godfrey,Jamie Rossjohn,James McCluskey

View Articletitled, A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition

Lineage specification and plasticity in CD19⁻ early B cell precursors

Lynn L. Rumfelt,Yan Zhou,Benjamin M. Rowley,Susan A. Shinton,Richard R. Hardy

View Articletitled, Lineage specification and plasticity in CD19− early B cell precursors

The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04

Rachelle Salomon,John Franks,Elena A. Govorkova,Natalia A. Ilyushina,Hui-Ling Yen,Diane J. Hulse-Post,Jennifer Humberd,Michel Trichet,Jerold E. Rehg,Richard J. Webby,Robert G. Webster,Erich Hoffmann

View Articletitled, The polymerase complex genes contribute to the high virulence of the human H5N1 influenza virus isolate A/Vietnam/1203/04

Structure and binding kinetics of three different human CD1d–α-galactosylceramide–specific T cell receptors

Stephan D. Gadola,Michael Koch,Jon Marles-Wright,Nikolai M. Lissin,Dawn Shepherd,Gediminas Matulis,Karl Harlos,Peter M. Villiger,David I. Stuart,Bent K. Jakobsen,Vincenzo Cerundolo,E. Yvonne Jones

View Articletitled, Structure and binding kinetics of three different human CD1d–α-galactosylceramide–specific T cell receptors

A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke

Judith Mallolas,Olivia Hurtado,Mar Castellanos,Miguel Blanco,Tomás Sobrino,Joaquín Serena,José Vivancos,José Castillo,Ignacio Lizasoain,María A. Moro,Antoni Dávalos

View Articletitled, A polymorphism in the EAAT2 promoter is associated with higher glutamate concentrations and higher frequency of progressing stroke

Orphan nuclear receptor TR3/Nur77 regulates VEGF-A–induced angiogenesis through its transcriptional activity

Huiyan Zeng,Liuliang Qin,Dezheng Zhao,Xiaolian Tan,Eleanor J. Manseau,Mien Van Hoang,Donald R. Senger,Lawrence F. Brown,Janice A. Nagy,Harold F. Dvorak

View Articletitled, Orphan nuclear receptor TR3/Nur77 regulates VEGF-A–induced angiogenesis through its transcriptional activity

Loss of the proapoptotic protein, Bim, breaks B cell anergy

Paula M. Oliver,Tibor Vass,John Kappler,Philippa Marrack

View Articletitled, Loss of the proapoptotic protein, Bim, breaks B cell anergy

Antibody isotype-specific engagement of Fcγ receptors regulates B lymphocyte depletion during CD20 immunotherapy

Yasuhito Hamaguchi,Yan Xiu,Kazuhiro Komura,Falk Nimmerjahn,Thomas F. Tedder

View Articletitled, Antibody isotype-specific engagement of Fcγ receptors regulates B lymphocyte depletion during CD20 immunotherapy

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

Takashi Usui,Jan C. Preiss,Yuka Kanno,Zheng Ju Yao,Jay H. Bream,John J. O'Shea,Warren Strober

View Articletitled, T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription

Systemic antithrombotic effects of ADAMTS13

Anil K. Chauhan,David G. Motto,Colin B. Lamb,Wolfgang Bergmeier,Michael Dockal,Barbara Plaimauer,Friedrich Scheiflinger,David Ginsburg,Denisa D. Wagner

View Articletitled, Systemic antithrombotic effects of ADAMTS13

Infected site-restricted Foxp3⁺ natural regulatory T cells are specific for microbial antigens

Isabelle J. Suffia,Stacie K. Reckling,Ciriaco A. Piccirillo,Romina S. Goldszmid,Yasmine Belkaid

View Articletitled, Infected site-restricted Foxp3+ natural regulatory T cells are specific for microbial antigens

Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

Yoshikatsu Kaneko,Falk Nimmerjahn,Michael P. Madaio,Jeffrey V. Ravetch

View Articletitled, Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors

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