Issues

People & Ideas

The Role of Innate Immunity in Autoimmunity

Jean-François Bach,Albert Bendelac,Michael B. Brenner,Harvey Cantor,Gennaro De Libero,Mitchell Kronenberg,Lewis L. Lanier,David H. Raulet,Mark J. Shlomchik,Matthias G. von Herrath
View Articletitled, The Role of Innate Immunity in Autoimmunity

Commentary

Finding a Place for Tumor-specific T Cells in Targeted Cancer Therapy

Stanley R. Riddell
View Articletitled, Finding a Place for Tumor-specific T Cells in Targeted Cancer Therapy

Article

Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking αvβ5 Integrin

Emeline F. Nandrot,Yoonhee Kim,Scott E. Brodie,Xiaozhu Huang,Dean Sheppard,Silvia C. Finnemann
View Articletitled, Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking αvβ5 Integrin

HIV-specific Cytotoxic T Cells from Long-Term Survivors Select a Unique T Cell Receptor

Tao Dong,Guillaume Stewart-Jones,Nan Chen,Philippa Easterbrook,Xiaoning Xu,Laura Papagno,Victor Appay,Michael Weekes,Chris Conlon,Celsa Spina,Susan Little,Gavin Screaton,Anton van der Merwe,Douglas D. Richman,Andrew J. McMichael,E. Yvonne Jones,Sarah L. Rowland-Jones
View Articletitled, HIV-specific Cytotoxic T Cells from Long-Term Survivors Select a Unique T Cell Receptor

Mycobacterium tuberculosis pks12 Produces a Novel Polyketide Presented by CD1c to T Cells

Isamu Matsunaga,Apoorva Bhatt,David C. Young,Tan-Yun Cheng,Stephen J. Eyles,Gurdyal S. Besra,Volker Briken,Steven A. Porcelli,Catherine E. Costello,William R. Jacobs, Jr.,D. Branch Moody
View Articletitled, <em>Mycobacterium tuberculosis pks12</em> Produces a Novel Polyketide Presented by CD1c to T Cells

Coordinated Redistribution of Leukocyte LFA-1 and Endothelial Cell ICAM-1 Accompany Neutrophil Transmigration

Sunil K. Shaw,Shuo Ma,Michael B. Kim,Ravi M. Rao,Charles U. Hartman,Richard M. Froio,Lin Yang,Todd Jones,Yuan Liu,Asma Nusrat,Charles A. Parkos,F. William Luscinskas
View Articletitled, Coordinated Redistribution of Leukocyte LFA-1 and Endothelial Cell ICAM-1 Accompany Neutrophil Transmigration

Reciprocal Changes in Tumor Antigenicity and Antigen-specific T Cell Function during Tumor Progression

Gang Zhou,Zhengbin Lu,John D. McCadden,Hyam I. Levitsky,Aimee L. Marson
View Articletitled, Reciprocal Changes in Tumor Antigenicity and Antigen-specific T Cell Function during Tumor Progression

CD8 Epitope Escape and Reversion in Acute HCV Infection

Joerg Timm,Georg M. Lauer,Daniel G. Kavanagh,Isabelle Sheridan,Arthur Y. Kim,Michaela Lucas,Thillagavathie Pillay,Kei Ouchi,Laura L. Reyor,Julian Schulze zur Wiesch,Rajesh T. Gandhi,Raymond T. Chung,Nina Bhardwaj,Paul Klenerman,Bruce D. Walker,Todd M. Allen
View Articletitled, CD8 Epitope Escape and Reversion in Acute HCV Infection

A Leishmania major Response Locus Identified by Interval-specific Congenic Mapping of a T Helper Type 2 Cell Bias-controlling Quantitative Trait Locus

Aurelie Baguet,Jennifer Epler,Kwun W. Wen,Mark Bix
View Articletitled, A <em>Leishmania major</em> Response Locus Identified by Interval-specific Congenic Mapping of a T Helper Type 2 Cell Bias-controlling Quantitative Trait Locus

Age-related Defects in CD4 T Cell Cognate Helper Function Lead to Reductions in Humoral Responses

Sheri M. Eaton,Eve M. Burns,Kimberly Kusser,Troy D. Randall,Laura Haynes
View Articletitled, Age-related Defects in CD4 T Cell Cognate Helper Function Lead to Reductions in Humoral Responses

Cytotoxic T Lymphocyte Therapy for Epstein-Barr Virus+ Hodgkin's Disease

Catherine M. Bollard,Laura Aguilar,Karin C. Straathof,Benedikt Gahn,M. Helen Huls,Alexandra Rousseau,John Sixbey,M. Victoria Gresik,George Carrum,Melissa Hudson,Dagmar Dilloo,Adrian Gee,Malcolm K. Brenner,Cliona M. Rooney,Helen E. Heslop
View Articletitled, Cytotoxic T Lymphocyte Therapy for Epstein-Barr Virus<sup>+</sup> Hodgkin's Disease

Intestinal Epithelial Cells Synthesize Glucocorticoids and Regulate T Cell Activation

Igor Cima,Nadia Corazza,Bernhard Dick,Andrea Fuhrer,Simon Herren,Sabine Jakob,Erick Ayuni,Christoph Mueller,Thomas Brunner
View Articletitled, Intestinal Epithelial Cells Synthesize Glucocorticoids and Regulate T Cell Activation

Anthrolysin O and Other Gram-positive Cytolysins Are Toll-like Receptor 4 Agonists

Jin Mo Park,Vincent H. Ng,Shin Maeda,Richard F. Rest,Michael Karin
View Articletitled, Anthrolysin O and Other Gram-positive Cytolysins Are Toll-like Receptor 4 Agonists

Down-regulation of Plasminogen Activator Inhibitor 1 Expression Promotes Myocardial Neovascularization by Bone Marrow Progenitors

Guosheng Xiang,Michael D. Schuster,Tetsunori Seki,Alfred A. Kocher,Shawdee Eshghi,Andrew Boyle,Silviu Itescu
View Articletitled, Down-regulation of Plasminogen Activator Inhibitor 1 Expression Promotes Myocardial Neovascularization by Bone Marrow Progenitors

Brief Definitive Report

Flavonoids Influence Monocytic GTPase Activity and Are Protective in Experimental Allergic Encephalitis

Jerome J.A. Hendriks,Jacqueline Alblas,Susanne M.A. van der Pol,Eric A.F. van Tol,Christine D. Dijkstra,Helga E. de Vries
View Articletitled, Flavonoids Influence Monocytic GTPase Activity and Are Protective in Experimental Allergic Encephalitis

Cadherin-11 Provides Specific Cellular Adhesion between Fibroblast-like Synoviocytes

Xavier Valencia,Jonathan M.G. Higgins,Hans P. Kiener,David M. Lee,Theresa A. Podrebarac,Christopher C. Dascher,Gerald F.M. Watts,Emiko Mizoguchi,Barry Simmons,Dhavalkumar D. Patel,Atul K. Bhan,Michael B. Brenner
View Articletitled, Cadherin-11 Provides Specific Cellular Adhesion between Fibroblast-like Synoviocytes

Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia

Tomoharu Yasuda,Masaki Shirakata,Atsushi Iwama,Asuka Ishii,Yasuhiro Ebihara,Mitsujiro Osawa,Kazuho Honda,Hisaaki Shinohara,Katsuko Sudo,Kohichiro Tsuji,Hiromitsu Nakauchi,Yoichiro Iwakura,Hisamaru Hirai,Hideaki Oda,Tadashi Yamamoto,Yuji Yamanashi
View Articletitled, Role of Dok-1 and Dok-2 in Myeloid Homeostasis and Suppression of Leukemia

Role of Dok-1 and Dok-2 in Leukemia Suppression

Masaru Niki,Antonio Di Cristofano,Mingming Zhao,Hiroaki Honda,Hisamaru Hirai,Linda Van Aelst,Carlos Cordon-Cardo,Pier Paolo Pandolfi
View Articletitled, Role of Dok-1 and Dok-2 in Leukemia Suppression