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Immunometabolism 2024

This collection explores the metabolic programing of immune cells, including T cells, neutrophils, microglia, macrophages, monocytes and hematopoietic progenitors, in cancer and metabolic diseases as well as during neuroinflammation and hematopoiesis.

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Article

TET2 promotes lung adeno-to-squamous transition

Yun Xue; Yuting Chen; Sijia Sun; Xinyuan Tong; Yujia Chen; Shijie Tang; Xue Wang; Simin Bi; Yuqin Qiu; Qiqi Zhao; Zhen Qin; Qin Xu; Yingjie Ai; Leilei Chen; Beizhen Zhang; Zhijie Liu; Minbiao Ji; Meidong Lang; Luonan Chen; Guoliang Xu; Liang Hu; Dan Ye; Hongbin Ji

https://doi.org/10.1084/jem.20240111

Article

Role of Ch25h in tau-mediated neurodegeneration

Danira Toral-Rios; Justin M. Long; Jason D. Ulrich; Jinsheng Yu; Michael R. Strickland; Xianlin Han; David M. Holtzman; Anil G. Cashikar; Steven M. Paul

https://doi.org/10.1084/jem.20232000

Review

Nutrients: Signal 4 in T cell immunity

Jana L. Raynor; Hongbo Chi

https://doi.org/10.1084/jem.20221839

Article

Eomes drives CD4⁺ T cell mitochondria–dependent survival

Emeline Joulia; Michaël F. Michieletto; Arantxa Agesta; Cindy Peillex; Virginie Girault; Anne-Louise Le Dorze; Romain Peroceschi; Florence Bucciarelli; Marion Szelechowski; Adeline Chaubet; Nawad Hakim; Rémi Marrocco; Emeline Lhuillier; Manuel Lebeurrier; Rafael J. Argüello; Abdelhadi Saoudi; Hicham El Costa; Veronique Adoue; Thierry Walzer; Jean-Emmanuel Sarry; Anne S. Dejean

https://doi.org/10.1084/jem.20230449

Article

Cholesterol overload to macrophages promotes NASH

Michiko Itoh; Atsushi Tamura; Sayaka Kanai; Miyako Tanaka; Yohei Kanamori; Ibuki Shirakawa; Ayaka Ito; Yasuyoshi Oka; Isao Hidaka; Taro Takami; Yasushi Honda; Mitsuyo Maeda; Yasuyuki Saito; Yoji Murata; Takashi Matozaki; Atsushi Nakajima; Yosky Kataoka; Tomoo Ogi; Yoshihiro Ogawa; Takayoshi Suganami

https://doi.org/10.1084/jem.20220681

Brief Definitive Report

TAOK3 regulates adipose tissue Tregs

Bastiaan Maes; Farzaneh Fayazpour; Leen Catrysse; Guillaume Lornet; Evelien Van De Velde; Caroline De Wolf; Sofie De Prijck; Justine Van Moorleghem; Manon Vanheerswynghels; Kim Deswarte; Benedicte Descamps; Christian Vanhove; Bart Van der Schueren; Roman Vangoitsenhoven; Hamida Hammad; Sophie Janssens; Bart N. Lambrecht

https://doi.org/10.1084/jem.20210788

Article

Metabolic requirements of myelopoiesis

Hannah A. Pizzato; Yahui Wang; Michael J. Wolfgang; Brian N. Finck; Gary J. Patti; Deepta Bhattacharya

https://doi.org/10.1084/jem.20221373

Article

Obesity alters monocyte states in cancer

Sheri A.C. McDowell; Simon Milette; Samuel Doré; Miranda W. Yu; Mark Sorin; Liam Wilson; Lysanne Desharnais; Alyssa Cristea; Ozgun Varol; Aline Atallah; Anikka Swaby; Valérie Breton; Azadeh Arabzadeh; Sarah Petrecca; Hamza Loucif; Aanya Bhagrath; Meghan De Meo; Katherine D. Lach; Marianne S.M. Issac; Benoit Fiset; Roni F. Rayes; Judith N. Mandl; Jörg H. Fritz; Pierre O. Fiset; Peter R. Holt; Andrew J. Dannenberg; Jonathan D. Spicer; Logan A. Walsh; Daniela F. Quail

https://doi.org/10.1084/jem.20220509

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Immunometabolism 2024

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