Three fractions have been isolated from autolysates of the meningococcus. Of these, one, the type-specific substance, has been described in detail. The same type-specific substance appears to be present in Type I and Type III organisms, but a substance differing at least serologically has been obtained from Type II strains. Detailed chemical analysis of both of the type-specific substances thus far isolated is being carried out and will be the subject of a later paper.

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