The experiments reported in this paper show that it is possible to render mice resistant to transplanted cancer by injections of a suitable quantity of olive oil. In the course of the development of the resistance a definite period of latency is detectable following the oil injection, and the maximum degree of resistance appears at about the 10th day. This state of resistance, as has been determined by histological studies, is preceded by a proliferation of the cells of the lymphoid germ centers and, after the cancer inoculation, is associated with a lymphoid infiltration about the grafts, as well as by a second stimulation of the lymphoid germ centers and an increase in the number of the circulating lymphocytes.
Article| April 01 1922
STUDIES ON LYMPHOID ACTIVITY : VI. IMMUNITY TO TRANSPLANTED CANCER INDUCED BY INJECTION OF OLIVE OIL.
From the Laboratories of The Rockefeller Institute for Medical Research.
Received: October 30 1921
Online Issn: 1540-9538
Print Issn: 0022-1007
Copyright, 1922, by The Rockefeller Institute for Medical Research New York
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Waro Nakahara; STUDIES ON LYMPHOID ACTIVITY : VI. IMMUNITY TO TRANSPLANTED CANCER INDUCED BY INJECTION OF OLIVE OIL. . J Exp Med 1 April 1922; 35 (4): 493–505. doi: https://doi.org/10.1084/jem.35.4.493
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