The experiments reported in this paper show that it is possible to render mice resistant to transplanted cancer by injections of a suitable quantity of olive oil. In the course of the development of the resistance a definite period of latency is detectable following the oil injection, and the maximum degree of resistance appears at about the 10th day. This state of resistance, as has been determined by histological studies, is preceded by a proliferation of the cells of the lymphoid germ centers and, after the cancer inoculation, is associated with a lymphoid infiltration about the grafts, as well as by a second stimulation of the lymphoid germ centers and an increase in the number of the circulating lymphocytes.

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