It has been found that some rabbits respond to the administration of either human C-reactive protein or human gamma globulin with the production of an acute phase substance, Cx-reactive protein. A correlation was found to exist between the amount of Cx-protein produced and the subsequent production of significant titers of precipitating antibody to the two antigens employed.
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Copyright, 1953, by The Rockefeller Institute for Medical Research New York
1953
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