Ligation of the cardiac end of the stomach or of the esophagus in ten dogs produced a severe toxemia, and rapid death.
In seven of the animals there occurred a marked rise in the total non-protein nitrogen and urea nitrogen of the blood.
The dogs living longest with cardiac obstruction showed a fall in blood chlorides and a rise in the CO2-combining power of the plasma. All the dogs with an obstruction of the esophagus showed a fall in blood chlorides.
Control animals subjected to other types of abdominal operations showed no significant changes in the blood.
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Copyright, 1923, by The Rockefeller Institute for Medical Research New York
1923
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