EPSTEIN-BARR VIRUS-NEGATIVE HUMAN MALIGNANT T-CELL LINES

Kaplan , Joseph; Shope , Thomas C.; Peterson , Ward D.

doi:10.1084/jem.139.5.1070

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Article| May 01 1974

EPSTEIN-BARR VIRUS-NEGATIVE HUMAN MALIGNANT T-CELL LINES

Joseph Kaplan,

Joseph Kaplan

From the Child Research Center of Michigan, Children's Hospital of Michigan, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201

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Thomas C. Shope,

Thomas C. Shope

From the Child Research Center of Michigan, Children's Hospital of Michigan, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201

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Ward D. Peterson, Jr.

From the Child Research Center of Michigan, Children's Hospital of Michigan, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201

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Author and Article Information

Joseph Kaplan

From the Child Research Center of Michigan, Children's Hospital of Michigan, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201

Thomas C. Shope

From the Child Research Center of Michigan, Children's Hospital of Michigan, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201

Ward D. Peterson, Jr.

From the Child Research Center of Michigan, Children's Hospital of Michigan, Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201

Received: January 21 1974

Online ISSN: 1540-9538

Print ISSN: 0022-1007

1974

J Exp Med (1974) 139 (5): 1070–1076.

https://doi.org/10.1084/jem.139.5.1070

Two lymphoblastoid lines, CCRF-CEM and HSB-2, with properties of malignant cells, derived from children with leukemia secondary to lymphosarcoma, have T-cell properties and lack Epstein-Barr virus antigens.

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