THE RENAL LESIONS OF ELECTROLYTE IMBALANCE II. THE COMBINED EFFECT ON RENAL ARCHITECTURE OF PHOSPHATE LOADING AND POTASSIUM DEPLETION

Holliday , M. A.; Winters , R. W.; Welt , L. G.; MacDowell , Muriel; Oliver , Jean

doi:10.1084/jem.110.2.161

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Article| August 01 1959

THE RENAL LESIONS OF ELECTROLYTE IMBALANCE : II. THE COMBINED EFFECT ON RENAL ARCHITECTURE OF PHOSPHATE LOADING AND POTASSIUM DEPLETION

M. A. Holliday,

M. A. Holliday

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

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R. W. Winters,

R. W. Winters

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

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L. G. Welt,

L. G. Welt

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

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Muriel MacDowell,

Muriel MacDowell

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

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Jean Oliver

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

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Author and Article Information

M. A. Holliday

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

R. W. Winters

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

L. G. Welt

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

Muriel MacDowell

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

Jean Oliver

From the Department of Pediatrics, Indiana University Medical Center, Department of Pediatrics and Department of Medicine, University of North Carolina, and the Renal Research Unit, Research Department, CIBA Pharmaceutical Products Inc., Summit, New Jersey

Received: February 23 1959

Online ISSN: 1540-9538

Print ISSN: 0022-1007

Copyright, 1959, by The Rockefeller Institute

1959

J Exp Med (1959) 110 (2): 161–168.

https://doi.org/10.1084/jem.110.2.161

Potassium depletion in rats augments the specific renal lesions of phosphate loading.

Since it has been shown that phosphate loading increases the specific cardiac lesions of potassium deficiency (12), it is concluded that the similar types of electrolyte imbalance (potassium depletion-phosphate load) act conversely in the two organs.

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Copyright, 1959, by The Rockefeller Institute

1959

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THE RENAL LESIONS OF ELECTROLYTE IMBALANCE : II. THE COMBINED EFFECT ON RENAL ARCHITECTURE OF PHOSPHATE LOADING AND POTASSIUM DEPLETION

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