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Journal Articles

Rag GTPases and mTORC1 regulate intestinal stem cell activity in response to nutrient availability

Weikang Fan, Churui Ge, Chunmei Niu, Shuang Liu, Peng Wang, Heng Li, Yang Cheng, Yingying Lu, Youheng Wei
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (9): e202510172.
https://doi.org/10.1083/jcb.202510172
Published: 13 July 2026
View article titled, Rag GTPases and mTORC1 regulate intestinal stem cell activity in response to nutrient availability
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Includes: Supplementary data
Journal Articles

Met-Vision reveals coexisting energetic states in tissue macrophages redistributed by inflammation

Adriana Lecourieux, Margot Bardou, Zacarias Garcia, Philippe Bousso
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (8): e202603170.
https://doi.org/10.1083/jcb.202603170
Published: 12 June 2026
View article titled, Met-Vision reveals coexisting energetic states in tissue macrophages redistributed by inflammation
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Journal Articles

Mitochondria limit coenzyme Q export under cholesterol biosynthetic stress

Marjana Ndoci, Sharanya Bhattacharya, Ishita Agrawal, Yvonne Hinze, Kathrin Lemke, Anna-Lena Schumacher, Esther Uijttewaal, Ulrich Elling, Steffen Lawo, Patrick Giavalisco, Thomas Langer, Soni Deshwal
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (8): e202507174.
https://doi.org/10.1083/jcb.202507174
Published: 08 June 2026
View article titled, Mitochondria limit coenzyme Q export under cholesterol biosynthetic stress
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Includes: Supplementary data
Journal Articles

Seipin: A central lipid rheostat

Abdou Rachid Thiam, Maxime Carpentier
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (7): e202602009.
https://doi.org/10.1083/jcb.202602009
Published: 03 June 2026
View article titled, Seipin: A central lipid rheostat
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Journal Articles

The environmental stress response regulates biophysics of the cytoplasm and survival in quiescence

Lorena Kronig, Carmen A. Weber, Pablo Aurelio Gómez-García, Jonas S. Fischer, Christian Doerig, Agnès Michel, Paolo Ronchi, Sarah Khawaja, Paola Picotti, Benoît Kornmann, Karsten Weis
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (6): e202601119.
https://doi.org/10.1083/jcb.202601119
Published: 30 April 2026
View article titled, The environmental stress response regulates biophysics of the cytoplasm and survival in quiescence
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Includes: Supplementary data
Journal Articles

Energy stress activates AMPK to arrest mitochondria via phosphorylation of TRAK1

Jill E. Falk, Tobias Henke, Sindhuja Gowrisankaran, Simone Wanderoy, Himanish Basu, Sinead Greally, Judith Steen, Thomas L. Schwarz
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (4): e202501023.
https://doi.org/10.1083/jcb.202501023
Published: 30 January 2026
View article titled, Energy stress activates AMPK to arrest mitochondria via phosphorylation of TRAK1
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Includes: Supplementary data
Journal Articles

Mechanometabolism of cell adhesion: Vinculin regulates bioenergetics via RhoA-ROCK

Emily D. Fabiano, Elle P. Techasiriwan, Lindsey N. Sabo, Nathaniel Seluga, Brenton D. Hoffman, Cynthia A. Reinhart-King
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (3): e202504025.
https://doi.org/10.1083/jcb.202504025
Published: 20 January 2026
View article titled, Mechanometabolism of cell adhesion: Vinculin regulates bioenergetics via RhoA-ROCK
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Includes: Supplementary data
Journal Articles

Potassium ion homeostasis modulates mitochondrial function

Adam James Waite, Beiduo Rao, Elizabeth Schinski, Nathaniel H. Thayer, Manuel Hotz, Austin E. Y. T. Lefebvre, Celeste Sandoval, Daniel E. Gottschling
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (4): e202505110.
https://doi.org/10.1083/jcb.202505110
Published: 13 January 2026
View article titled, Potassium ion homeostasis modulates mitochondrial function
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Includes: Supplementary data
Journal Articles

Mitochondrial presequences harbor variable strengths to maintain organellar function

Youmian Yan, Baigalmaa Erdenepurev, Thiago N. Menezes, Ian Collinson, Natalie M. Niemi
Journal: Journal of Cell Biology
J Cell Biol (2026) 225 (4): e202507116.
https://doi.org/10.1083/jcb.202507116
Published: 08 January 2026
View article titled, Mitochondrial presequences harbor variable strengths to maintain organellar function
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Includes: Supplementary data
Journal Articles

Irg1l regulates neuromast size via metabolic reprogramming to promote supporting cell proliferation

Xin Wang, Ruijun Shi, Yuqing Xiang, Yajing Gao, Guoqiang Wan, Shan Sun, Dong Liu
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (12): e202501122.
https://doi.org/10.1083/jcb.202501122
Published: 28 October 2025
View article titled, Irg1l regulates neuromast size via metabolic reprogramming to promote supporting cell proliferation
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Includes: Supplementary data
Journal Articles

Lipid droplets: Open questions and conceptual advances around a unique organelle

W. Mike Henne, Emma Reynolds, William A. Prinz
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (10): e202406019.
https://doi.org/10.1083/jcb.202406019
Published: 11 September 2025
View article titled, Lipid droplets: Open questions and conceptual advances around a unique organelle
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Journal Articles

Mechanisms of genome instability from cellular folate stress

Christopher Mellor, Elisabeth A. Larson, Meng Wang
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (9): e202502205.
https://doi.org/10.1083/jcb.202502205
Published: 18 August 2025
View article titled, Mechanisms of genome instability from cellular folate stress
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Journal Articles

The yeast Mkt1/Pbp1 complex promotes adaptive responses to respiratory growth

Daniel Caballero, Benjamin M. Sutter, Zheng Xing, Caroline Wang, Emma Choo, Yun Wang, Yu-San Yang, Sina Ghaemmaghami, Andrew Lemoff, Benjamin P. Tu
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (10): e202411169.
https://doi.org/10.1083/jcb.202411169
Published: 13 August 2025
View article titled, The yeast Mkt1/Pbp1 complex promotes adaptive responses to respiratory growth
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Includes: Supplementary data
Journal Articles

New insights into lipid droplet breakdown in alcohol-associated hepatic steatosis

Chen Zhang, Wen-Xing Ding
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (8): e202506103.
https://doi.org/10.1083/jcb.202506103
Published: 29 July 2025
View article titled, New insights into lipid droplet breakdown in alcohol-associated hepatic steatosis
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Journal Articles

An ethanol-induced loss of the lipid droplet–associated segregase VCP/p97 leads to hepatic steatosis

Sandhya Sen, Shaun Weller, Ryan J. Schulze, Donglin Ding, Carol A. Casey, Conrad Weihl, Mark A. McNiven
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (8): e202408205.
https://doi.org/10.1083/jcb.202408205
Published: 29 July 2025
View article titled, An ethanol-induced loss of the lipid droplet–associated segregase VCP/p97 leads to hepatic steatosis
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Includes: Supplementary data
Journal Articles

Acidosis attenuates the hypoxic stabilization of HIF-1α by activating lysosomal degradation

Bobby White, Zhenyi Wang, Matthew Dean, Johanna Michl, Natalia Nieora, Sarah Flannery, Iolanda Vendrell, Roman Fischer, Alzbeta Hulikova, Pawel Swietach
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (8): e202409103.
https://doi.org/10.1083/jcb.202409103
Published: 24 June 2025
View article titled, Acidosis attenuates the hypoxic stabilization of HIF-1α by activating lysosomal degradation
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Includes: Supplementary data
Journal Articles

ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the Fanconi anemia pathway

In Special Collection:
Cancer Cell Biology 2026
Moonjung Jung, Jungwoo Kim, Yeji Park, Isaac Ilyashov, Fan Yang, Haruna B. Choijilsuren, Danielle Keahi, Jordan A. Durmaz, Habin Bea, Audrey M. Goldfarb, Mia D. Stein, Claudia Wong, Ryan R. White, Sunandini Sridhar, Raymond Noonan, Tom F. Wiley, Thomas S. Carroll, Francis P. Lach, Sangmoo Jeong, Ileana C. Miranda, Agata Smogorzewska
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (7): e202407141.
https://doi.org/10.1083/jcb.202407141
Published: 20 June 2025
View article titled, ALDH9A1 deficiency as a source of endogenous DNA damage that requires repair by the Fanconi anemia pathway
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Includes: Supplementary data
Journal Articles

The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1

Aiko Watanabe, Shizuka Ogiwara, Mirei Saito, Masaki Mishima, Masahiro Yamashina, Ryuichiro Ishitani, Yutaka Ito, Keiji Tanaka, Fumika Koyano, Koji Yamano, Hidetaka Kosako, Yoshitaka Moriwaki, Noriyuki Matsuda
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (8): e202411078.
https://doi.org/10.1083/jcb.202411078
Published: 04 June 2025
View article titled, The reaction mechanism for glycolysis side product degradation by Parkinson’s disease–linked DJ-1
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Includes: Supplementary data
Journal Articles

Mitochondrial mayhem: Disrupting conserved N-terminal motifs in TANGO2 impacts its localization and function

Sarah E. Sandkuhler, Samuel J. Mackenzie
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (5): e202503010.
https://doi.org/10.1083/jcb.202503010
Published: 15 April 2025
View article titled, Mitochondrial mayhem: Disrupting conserved N-terminal motifs in TANGO2 impacts its localization and function
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Journal Articles

TANGO2 is an acyl-CoA binding protein

Agustin Leonardo Lujan, Ombretta Foresti, Jose Wojnacki, Gonzalo Bigliani, Nathalie Brouwers, Maria Jesus Pena, Stefania Androulaki, Tomomi Hashidate-Yoshida, Maria Kalyukina, Sergey S. Novoselov, Hideo Shindou, Vivek Malhotra
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (5): e202410001.
https://doi.org/10.1083/jcb.202410001
Published: 27 February 2025
View article titled, TANGO2 is an acyl-CoA binding protein
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Includes: Supplementary data

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