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Surface Morphometrics reveals local membrane thickness variation in organellar subcompartments

Michaela Medina, Ya-Ting Chang, Hamidreza Rahmani, Mark Frank, Zidan Khan, Daniel Fuentes, Frederick A. Heberle, M. Neal Waxham, Benjamin A. Barad, Danielle A. Grotjahn

J Cell Biol (2025) 225 (3): e202505059.

https://doi.org/10.1083/jcb.202505059

Published: 26 December 2025

View article titled, Surface Morphometrics reveals local membrane thickness variation in organellar subcompartments

Journal Articles

Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis

Heitor Gobbi Sebinelli, Camille Syska, Hafez Razmazma, Véronique Albanèse, Ana Rita Dias Araujo, Cecile Hilpert, Cédric Montigny, Christine Jaxel, Manuella Tchamba, Karolina Belingar, Juan Martín D’Ambrosio, Luca Monticelli, Guillaume Lenoir, Alenka Čopič

J Cell Biol (2025) 225 (2): e202502112.

https://doi.org/10.1083/jcb.202502112

Published: 26 December 2025

View article titled, Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis

Includes: Supplementary data

Journal Articles

Separating chromosomes, one way or another

Bonnibelle K. Leeds, Charles L. Asbury

J Cell Biol (2025) 225 (1): e202512084.

https://doi.org/10.1083/jcb.202512084

Published: 26 December 2025

View article titled, Separating chromosomes, one way or another

Journal Articles

Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion

Evgenia Leikina, Andrey K. Tsaturyan, Kamran Melikov, Jarred M. Whitlock, Jared Cunanan, Morgan Roegner, Griffin Katz, Michael M. Kozlov, Leonid V. Chernomordik

J Cell Biol (2025) 225 (2): e202508055.

https://doi.org/10.1083/jcb.202508055

Published: 02 December 2025

View article titled, Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion

Includes: Supplementary data

Journal Articles

High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation

Xun Cao, Yiming Peng, Mengyuan Yang, Mengling Gan, Di Zhang, Shiyue Zhou, Daisuke Takao

J Cell Biol (2025) 225 (1): e202503083.

https://doi.org/10.1083/jcb.202503083

Published: 14 November 2025

View article titled, High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation

Includes: Supplementary data

Journal Articles

Understanding microtubule dynamics: The synergy of technology, theory, and experiment

J. Richard McIntosh

J Cell Biol (2025) 224 (11): e202505046.

https://doi.org/10.1083/jcb.202505046

Published: 15 October 2025

View article titled, Understanding microtubule dynamics: The synergy of technology, theory, and experiment

Journal Articles

Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis

Kirstin R. Rollins, Sareen Fiaz, Ishwaree Datta, Meghan A. Morrissey

J Cell Biol (2025) 224 (11): e202502034.

https://doi.org/10.1083/jcb.202502034

Published: 03 October 2025

View article titled, Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis

Includes: Supplementary data

Journal Articles

Patterning in motion: Cell interfaces guide mesenchymal collective migration and morphogenesis

Maik C. Bischoff, Roberto Mayor

J Cell Biol (2025) 224 (11): e202505198.

https://doi.org/10.1083/jcb.202505198

Published: 23 September 2025

View article titled, Patterning in motion: Cell interfaces guide mesenchymal collective migration and morphogenesis

Journal Articles

Multi-kinesin clusters impart mechanical stress that reveals mechanisms of microtubule breakage in cells

Qi Geng, Andres Bonilla, Siara N. Sandwith, Kristen J. Verhey

J Cell Biol (2025) 224 (10): e202501070.

https://doi.org/10.1083/jcb.202501070

Published: 11 August 2025

View article titled, Multi-kinesin clusters impart mechanical stress that reveals mechanisms of microtubule breakage in cells

Journal Articles

AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact

Benjamin S. Padman, Runa S.J. Lindblom, Michael Lazarou

J Cell Biol (2025) 224 (10): e202411138.

https://doi.org/10.1083/jcb.202411138

Published: 30 July 2025

View article titled, AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact

Journal Articles

STIM-IP3R crosstalk regulates migration of breast cancer cells

Ruslana Militsin, Hadas Achildiev Cohen, Maya Hershfinkel, Ofek Levi, Stavit Drori, Adi Yifat Raz, Yuval Shaked, Raz Palty

J Cell Biol (2025) 224 (9): e202411203.

https://doi.org/10.1083/jcb.202411203

Published: 28 July 2025

View article titled, STIM-IP3R crosstalk regulates migration of breast cancer cells

Includes: Supplementary data

Journal Articles

Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis

Emmanuel T. Nsamba, Abesh Bera, Vaishali Todi, Landon Savoy, Ryan M. Gupta, Mohan L. Gupta, Jr.

J Cell Biol (2025) 224 (9): e202301115.

https://doi.org/10.1083/jcb.202301115

Published: 25 July 2025

View article titled, Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis

Includes: Supplementary data

Journal Articles

WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation

Muziyue Wu, Raj Kumar Sadhu, Kirstin Meyer, Ziqi Tang, Paul Marchando, Derek N. Woolfson, Nir S. Gov, Orion D. Weiner

J Cell Biol (2025) 224 (9): e202410098.

https://doi.org/10.1083/jcb.202410098

Published: 16 July 2025

View article titled, WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation

Includes: Supplementary data

Journal Articles

The PAX3-FOXO1 fusion gene reduces cell–ECM interactions and TGFβ signaling in rhabdomyosarcoma

Antonios Chronopoulos, Ivan Chavez, Chandra Kaladhar Vemula, Nikhil Mittal, Vic Zamloot, Yuanzhong Pan, Sangyoon J. Han, JinSeok Park

J Cell Biol (2025) 224 (7): e202408155.

https://doi.org/10.1083/jcb.202408155

Published: 30 June 2025

View article titled, The PAX3-FOXO1 fusion gene reduces cell–ECM interactions and TGFβ signaling in rhabdomyosarcoma

Includes: Supplementary data

Journal Articles

Dynamic interaction of spliceosomal snRNPs with coilin explains Cajal body characteristics

Davide A. Basello, Michaela Blažíková, Adriana Roithová, Martina Hálová, Nenad Radivojević, Karla M. Neugebauer, David Staněk

J Cell Biol (2025) 224 (8): e202309128.

https://doi.org/10.1083/jcb.202309128

Published: 25 June 2025

View article titled, Dynamic interaction of spliceosomal snRNPs with coilin explains Cajal body characteristics

Includes: Supplementary data

Journal Articles

Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins

Yumeng Wan, Yuri L. Nemoto, Tsukasa Oikawa, Kazunori Takano, Takahiro K. Fujiwara, Kazuya Tsujita, Toshiki Itoh

J Cell Biol (2025) 224 (7): e202411024.

https://doi.org/10.1083/jcb.202411024

Published: 08 May 2025

View article titled, Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins

Includes: Supplementary data

Journal Articles

Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin

Tatsuki Isogai, Koichiro M. Hirosawa, Miki Kanno, Ayano Sho, Rinshi S. Kasai, Naoko Komura, Hiromune Ando, Keiko Furukawa, Yuhsuke Ohmi, Koichi Furukawa, Yasunari Yokota, Kenichi G.N. Suzuki

J Cell Biol (2025) 224 (6): e202404064.

https://doi.org/10.1083/jcb.202404064

Published: 30 April 2025

View article titled, Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin

Includes: Supplementary data

Journal Articles

Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping

Tsukasa Makino, Ryo Kanada, Teppei Mori, Ken-ichi Miyazono, Yuta Komori, Haruaki Yanagisawa, Shoji Takada, Masaru Tanokura, Masahide Kikkawa, Michio Tomishige

J Cell Biol (2025) 224 (7): e202501253.

https://doi.org/10.1083/jcb.202501253

Published: 29 April 2025

View article titled, Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping

Journal Articles

CCSer2 gates dynein activity at the cell periphery

Juliana L. Zang, Daytan Gibson, Ann-Marie Zheng, Wanjing Shi, John P. Gillies, Chris Stein, Catherine M. Drerup, Morgan E. DeSantis

J Cell Biol (2025) 224 (6): e202406153.

https://doi.org/10.1083/jcb.202406153

Published: 22 April 2025

View article titled, CCSer2 gates dynein activity at the cell periphery

Includes: Supplementary data

Journal Articles

Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome

Alexandre Schaeffer, Simona Buracco, Morgan Gazzola, Matthieu Gelin, Benoit Vianay, Chiara de Pascalis, Laurent Blanchoin, Manuel Théry

J Cell Biol (2025) 224 (7): e202405126.

https://doi.org/10.1083/jcb.202405126

Published: 17 April 2025

View article titled, Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome

Includes: Supplementary data

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Surface Morphometrics reveals local membrane thickness variation in organellar subcompartments

Ist2 is a phospholipid scramblase that links lipid transport at the ER to organelle homeostasis

Separating chromosomes, one way or another

Phosphatidylserine exposure and annexin A5 weaken the actin cortex in osteoclast fusion

High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation

Understanding microtubule dynamics: The synergy of technology, theory, and experiment

Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis

Patterning in motion: Cell interfaces guide mesenchymal collective migration and morphogenesis

Multi-kinesin clusters impart mechanical stress that reveals mechanisms of microtubule breakage in cells

AI-directed voxel extraction and volume EM identify intrusions as sites of mitochondrial contact

STIM-IP3R crosstalk regulates migration of breast cancer cells

Tubulin isotypes contribute opposing properties to balance anaphase spindle morphogenesis

WAVE complex forms linear arrays at negative membrane curvature to instruct lamellipodia formation

The PAX3-FOXO1 fusion gene reduces cell–ECM interactions and TGFβ signaling in rhabdomyosarcoma

Dynamic interaction of spliceosomal snRNPs with coilin explains Cajal body characteristics

Mechanical control of osteoclast fusion by membrane-cortex attachment and BAR proteins

Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin

Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping

CCSer2 gates dynein activity at the cell periphery

Microtubule-driven cell shape changes and actomyosin flow synergize to position the centrosome

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