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Journal Articles

Is the Parkinson’s-associated protein TMEM175 a proton channel: Yay or nay?

Spencer A. Freeman, Sergio Grinstein

J Cell Biol (2025) 225 (1): e202511084.

https://doi.org/10.1083/jcb.202511084

Published: 26 November 2025

View article titled, Is the Parkinson’s-associated protein TMEM175 a proton channel: Yay or nay?

Journal Articles

Homocysteine disrupts lysosomal function by V-ATPase inhibition

Yang Yang, Qianjin Kong, Chaolian Liu, Fengyang Wang, Meijiao Li, Shalan Li, Yuehui Shi, Leonard Krall, Xin Wang, Shan He, Kai Jiang, Xuna Wu, Mei Yang, Chonglin Yang

J Cell Biol (2025) 225 (1): e202503081.

https://doi.org/10.1083/jcb.202503081

Published: 25 November 2025

View article titled, Homocysteine disrupts lysosomal function by V-ATPase inhibition

Includes: Supplementary data

Journal Articles

Bacterial CipB is an exogenous receptor to drive the mitophagy-TFEB axis and promote pathogenesis

Shuai Liu, Lina Ma, Ruiqi Lv, Liangting Guo, Xing Pan, Shufan Hu, Shan Li

J Cell Biol (2025) 225 (1): e202503028.

https://doi.org/10.1083/jcb.202503028

Published: 21 November 2025

View article titled, Bacterial CipB is an exogenous receptor to drive the mitophagy-TFEB axis and promote pathogenesis

Includes: Supplementary data

Journal Articles

Talin–tensin3 interactions regulate fibrillar adhesion formation and tensin3 phase separation

Xingchen Li, Rafaella Konstantinou, Vinod Kumar Meena, Saba Notash, Komal Khalil, Tom Whalley, Paul Atherton, Igor Barsukov, Thomas Zacharchenko, Christoph Ballestrem

J Cell Biol (2025) 225 (1): e202503155.

https://doi.org/10.1083/jcb.202503155

Published: 21 November 2025

View article titled, Talin–tensin3 interactions regulate fibrillar adhesion formation and tensin3 phase separation

Includes: Supplementary data

Journal Articles

Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis

Nicolas Joly, Lionel Pintard

J Cell Biol (2025) 225 (2): e202506192.

https://doi.org/10.1083/jcb.202506192

Published: 19 November 2025

View article titled, Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis

Includes: Supplementary data

Journal Articles

Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis

Tianqi Wang, Daniel H. Kim, Chang Ding, Dingxun Wang, Weiwei Zhang, Martin Silic, Xi Cheng, Kunming Shao, TingHsuan Ku, Conwy Zheng, Junkai Xie, Shulan Xiao, Krishna Jayant, Chongli Yuan, Alexander A. Chubykin, Christopher J. Staiger, GuangJun Zhang, Qing Deng

J Cell Biol (2025) 225 (1): e202503037.

https://doi.org/10.1083/jcb.202503037

Published: 19 November 2025

View article titled, Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis

Includes: Supplementary data

Journal Articles

A new probe illuminates endo-lysosomal Ca²⁺ measurements: A role for vesicular IP₃ receptors?

Anthony J. Morgan

J Cell Biol (2025) 224 (12): e202511020.

https://doi.org/10.1083/jcb.202511020

Published: 17 November 2025

View article titled, A new probe illuminates endo-lysosomal Ca2+ measurements: A role for vesicular IP3 receptors?

Journal Articles

High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation

Xun Cao, Yiming Peng, Mengyuan Yang, Mengling Gan, Di Zhang, Shiyue Zhou, Daisuke Takao

J Cell Biol (2025) 225 (1): e202503083.

https://doi.org/10.1083/jcb.202503083

Published: 14 November 2025

View article titled, High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation

Includes: Supplementary data

Journal Articles

Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation

Clyde Savio Pinto, Saskia E. Bakker, Andrejus Suchenko, Isabella M. Kolodny, Hamdi Hussain, Tomoyuki Hatano, Karuna Sampath, Krishna Chinthalapudi, Sarah M. Heissler, Masanori Mishima, Mohan Balasubramanian

J Cell Biol (2025) 225 (1): e202409067.

https://doi.org/10.1083/jcb.202409067

Published: 14 November 2025

View article titled, Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation

Includes: Supplementary data

Journal Articles

Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion

Camilla S. Teng, Sarah W. Curtis, Grace C. Brewer, Elizabeth J. Leslie-Clarkson, Jeffrey O. Bush

J Cell Biol (2025) 225 (1): e202503070.

https://doi.org/10.1083/jcb.202503070

Published: 13 November 2025

View article titled, Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion

Includes: Supplementary data

Journal Articles

Sensing danger at the bridge

Juan Martin-Serrano

J Cell Biol (2025) 224 (12): e202509237.

https://doi.org/10.1083/jcb.202509237

Published: 12 November 2025

View article titled, Sensing danger at the bridge

Journal Articles

Reevaluating the roles of PPARs and nuclear receptors in human peroxisome biology

Fred D. Mast, Richard A. Rachubinski, John D. Aitchison

J Cell Biol (2025) 224 (12): e202506162.

https://doi.org/10.1083/jcb.202506162

Published: 11 November 2025

View article titled, Reevaluating the roles of PPARs and nuclear receptors in human peroxisome biology

Journal Articles

Adapting plasma membrane for mitotic cell rounding through Aurora A phosphorylation of numb

Yanyan Li, Ke Liu, Xian Lin, Zhihao Ding, Haiyan Sun, Xiangyun Liao, Binghua Cheng, Wenli Shi, Junde Xu, Jiaming Liang, Zeyu Zhou, Wenjie Zhou, Hui Tian, Long Meng, Guangyong Chen, Ximing Shao, Hongchang Li

J Cell Biol (2025) 224 (12): e202412005.

https://doi.org/10.1083/jcb.202412005

Published: 10 November 2025

View article titled, Adapting plasma membrane for mitotic cell rounding through Aurora A phosphorylation of numb

Includes: Supplementary data

Journal Articles

Direct measurements of luminal Ca²⁺ with endo-lysosomal GFP-aequorin reveal functional IP₃ receptors

Belén Calvo, Patricia Torres-Vidal, Alba Delrio-Lorenzo, Carla Rodriguez, Francisco J. Aulestia, Jonathan Rojo-Ruiz, Beatriz Callejo, Bridget M. McVeigh, Marco Keller, Christian Grimm, Viola Oorschot, Vera Moiseenkova-Bell, David I. Yule, Javier Garcia-Sancho, Sandip Patel, M. Teresa Alonso

J Cell Biol (2025) 224 (12): e202410094.

https://doi.org/10.1083/jcb.202410094

Published: 07 November 2025

View article titled, Direct measurements of luminal Ca2+ with endo-lysosomal GFP-aequorin reveal functional IP3 receptors

Includes: Supplementary data

Journal Articles

Bni5 regulates and coordinates septin architecture and myosin-II functions at the cell division site

Hiroki Okada, Xi Chen, Joseph Marquardt, Kangji Wang, Erfei Bi

J Cell Biol (2025) 224 (12): e202311040.

https://doi.org/10.1083/jcb.202311040

Published: 06 November 2025

View article titled, Bni5 regulates and coordinates septin architecture and myosin-II functions at the cell division site

Includes: Supplementary data

Journal Articles

Contact-dependent incorporation of endoplasmic reticulum into retraction fibers and migrasomes

Peiyao Fan, Rui Ji, Yiling Wen, Yaping Dang, Yong Li, Xiaojie Yan, Murong Li, Qiaoxia Zheng, Yifan Ge, Pengli Zheng, Yang Chen

J Cell Biol (2025) 224 (12): e202505064.

https://doi.org/10.1083/jcb.202505064

Published: 06 November 2025

View article titled, Contact-dependent incorporation of endoplasmic reticulum into retraction fibers and migrasomes

Includes: Supplementary data

Journal Articles

RTF1 enhances CLK occupancy and histone methylation at key circadian clock pacemaker gene loci

Xu Liu, Ya Huang, Jiajia Fang, Xianli He, Yue Zhou, Wei Luan, Xianhui Liu, Yong Zhang

J Cell Biol (2025) 224 (12): e202501221.

https://doi.org/10.1083/jcb.202501221

Published: 04 November 2025

View article titled, RTF1 enhances CLK occupancy and histone methylation at key circadian clock pacemaker gene loci

Includes: Supplementary data

Journal Articles

Autoinhibitory calcium ATPases regulate the calcium gradient required for rapid polarized growth

Samantha E. Ryken, Shu-Zon Wu, Matias L. Lee, Miranda M. Greig, Nika M. Recto, Sophia Chang Stauffer, Carlisle S. Bascom, Jr., Eric M. Kramer, Magdalena Bezanilla

J Cell Biol (2025) 225 (1): e202506021.

https://doi.org/10.1083/jcb.202506021

Published: 04 November 2025

View article titled, Autoinhibitory calcium ATPases regulate the calcium gradient required for rapid polarized growth

Includes: Supplementary data

Journal Articles

Systematic membrane thickness variation across cellular organelles revealed by cryo-ET

Desislava Glushkova, Stefanie Böhm, Martin Beck

J Cell Biol (2025) 225 (1): e202504053.

https://doi.org/10.1083/jcb.202504053

Published: 04 November 2025

View article titled, Systematic membrane thickness variation across cellular organelles revealed by cryo-ET

Journal Articles

B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface

Xinyang Li, Yue Hua, Jiahui Wang, Mengxiao Wu, Yu Pan, Jiyong Wang, Xiaoqing Gan

J Cell Biol (2025) 224 (12): e202501170.

https://doi.org/10.1083/jcb.202501170

Published: 03 November 2025

View article titled, B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface

Includes: Supplementary data

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Is the Parkinson’s-associated protein TMEM175 a proton channel: Yay or nay?

Homocysteine disrupts lysosomal function by V-ATPase inhibition

Bacterial CipB is an exogenous receptor to drive the mitophagy-TFEB axis and promote pathogenesis

Talin–tensin3 interactions regulate fibrillar adhesion formation and tensin3 phase separation

Intramolecular regulation of the MT-severing enzyme Katanin prevents futile ATP hydrolysis

Inwardly rectifying potassium channels promote directional sensing during neutrophil chemotaxis

A new probe illuminates endo-lysosomal Ca²⁺ measurements: A role for vesicular IP₃ receptors?

High-content phenotyping reveals Golgi dynamics and their role in cell cycle regulation

Actin arginylation alters myosin engagement and F-actin patterning despite structural conservation

Actomyosin contractility and a threshold of cadherin cell adhesion are required during tissue fusion

Sensing danger at the bridge

Reevaluating the roles of PPARs and nuclear receptors in human peroxisome biology

Adapting plasma membrane for mitotic cell rounding through Aurora A phosphorylation of numb

Direct measurements of luminal Ca²⁺ with endo-lysosomal GFP-aequorin reveal functional IP₃ receptors

Bni5 regulates and coordinates septin architecture and myosin-II functions at the cell division site

Contact-dependent incorporation of endoplasmic reticulum into retraction fibers and migrasomes

RTF1 enhances CLK occupancy and histone methylation at key circadian clock pacemaker gene loci

Autoinhibitory calcium ATPases regulate the calcium gradient required for rapid polarized growth

Systematic membrane thickness variation across cellular organelles revealed by cryo-ET

B4GALT1 and Wntless collaborate to block LRP5/6 translocation from Golgi to cell surface

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