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PI(3)P regulates mitochondrial dynamics through EXC-5–dependent actin remodeling

Sneha Hegde, Marc Germain

J Cell Biol (2026) 225 (6): e202603198.

https://doi.org/10.1083/jcb.202603198

Published: 14 May 2026

View article titled, PI(3)P regulates mitochondrial dynamics through EXC-5–dependent actin remodeling

Journal Articles

Chromosome segregation synchrony in S. pombe is noise limited and arises without positive feedback

Wendi Williams, Kien Phan, Jing Chen, Stefan Legewie, Julia Kamenz, Silke Hauf

J Cell Biol (2026) 225 (7): e202602088.

https://doi.org/10.1083/jcb.202602088

Published: 14 May 2026

View article titled, Chromosome segregation synchrony in S. pombe is noise limited and arises without positive feedback

Includes: Supplementary data

Journal Articles

Eosinophils promote a second wave of postnatal smooth muscle differentiation in intestinal villi

Tatiana V. Petrova, Kelly de Korodi, Thea Berg, Tania Wyss, Yahya Mohammadzadeh, Lida Safazada, Kathleen Shah, Nicola L. Harris, Jeremiah Bernier-Latmani

J Cell Biol (2026) 225 (7): e202505012.

https://doi.org/10.1083/jcb.202505012

Published: 12 May 2026

View article titled, Eosinophils promote a second wave of postnatal smooth muscle differentiation in intestinal villi

Includes: Supplementary data

Journal Articles

Neutrophil serine proteases degrade endothelial cortactin and promote extravasation

Idaira M. Guerrero-Fonseca, Karina B. Hernández-Almaraz, Iliana I. León-Vega, Régis Joulia, Armando Montoya-García, Hilda Vargas-Robles, Theresia E.B. Stradal, Klemens Rottner, Reyna Oregon, Eduardo Vadillo, Jennifer L. Johnson, William B. Kiosses, Sergio D. Catz, Sussan Nourshargh, Michael Schnoor

J Cell Biol (2026) 225 (7): e202410019.

https://doi.org/10.1083/jcb.202410019

Published: 12 May 2026

View article titled, Neutrophil serine proteases degrade endothelial cortactin and promote extravasation

Includes: Supplementary data

Journal Articles

A deep dive into functional ribosome specialization

Seohyun Park, Fiona Fitzgerald, Yoon-Mo Yang, Katrin Karbstein

J Cell Biol (2026) 225 (6): e202511091.

https://doi.org/10.1083/jcb.202511091

Published: 12 May 2026

View article titled, A deep dive into functional ribosome specialization

Journal Articles

Mitochondrially tethered Mmm1 can function as a sole lipid transporter at ER–mitochondria contacts

Christian Covill-Cooke, Takashi Hirashima, Shin Kawano, Joe Ganellin, Andrew Moody, Sabine N.S. van Schie, Arun T. John Peter, Chika Horie Saito, Toshiya Endo, Benoît Kornmann

J Cell Biol (2026) 225 (7): e202411196.

https://doi.org/10.1083/jcb.202411196

Published: 07 May 2026

View article titled, Mitochondrially tethered Mmm1 can function as a sole lipid transporter at ER–mitochondria contacts

Includes: Supplementary data

Journal Articles

Disruption of macrophage cell volume drives inflammatory responses and type I interferon signaling

James R. Cook, Tara A. Gleeson, Sara Gago, Stuart M. Allan, Kevin N. Couper, Catherine B. Lawrence, David Brough, Jack P. Green

J Cell Biol (2026) 225 (6): e202411133.

https://doi.org/10.1083/jcb.202411133

Published: 07 May 2026

View article titled, Disruption of macrophage cell volume drives inflammatory responses and type I interferon signaling

Includes: Supplementary data

Journal Articles

Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development

Anna R. Yeh, Gregory J. Hoeprich, Anthony D. McDougal, Bruce L. Goode, Adam C. Martin

J Cell Biol (2026) 225 (7): e202306071.

https://doi.org/10.1083/jcb.202306071

Published: 06 May 2026

View article titled, Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development

Includes: Supplementary data

Journal Articles

NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis

Mohit Das, Eli Coronado-Chavez, Anusha D. Bhatt, Reyhaneh Tirgar, Amanda A. Amodeo, Jared T. Nordman

J Cell Biol (2026) 225 (7): e202511182.

https://doi.org/10.1083/jcb.202511182

Published: 06 May 2026

View article titled, NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis

Includes: Supplementary data

Journal Articles

Phosphatidylserine is a component of the gradient-tracking machine in mating yeast

Chih-Yu Pai, Xin Wang, Hamida Mahmood, David E. Stone

J Cell Biol (2026) 225 (6): e202504130.

https://doi.org/10.1083/jcb.202504130

Published: 05 May 2026

View article titled, Phosphatidylserine is a component of the gradient-tracking machine in mating yeast

Includes: Supplementary data

Journal Articles

Optogenetic control of PLC-γ1 activity directs cell motility

Ravikanth Appalabhotla, Priscila F. Siesser, Harrison Truscott, Nicole Hajicek, John Sondek, James E. Bear, Jason M. Haugh

J Cell Biol (2026) 225 (7): e202507177.

https://doi.org/10.1083/jcb.202507177

Published: 05 May 2026

View article titled, Optogenetic control of PLC-γ1 activity directs cell motility

Includes: Supplementary data

Journal Articles

LGL-1 and the RhoGAP protein PAC-1 redundantly polarize the Caenorhabditis elegans embryonic epidermis

Olga D. Jarosińska, Amalia Riga, Hala Zahreddine Fahs, Joren M. Woeltjes, Ruben Schmidt, Fathima S. Refai, Suma Gopinadhan, Kristin C. Gunsalus, Mike Boxem

J Cell Biol (2026) 225 (6): e202601031.

https://doi.org/10.1083/jcb.202601031

Published: 05 May 2026

View article titled, LGL-1 and the RhoGAP protein PAC-1 redundantly polarize the Caenorhabditis elegans embryonic epidermis

Includes: Supplementary data

Journal Articles

Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy

Matthew Domenic Lycas, Dustin R. Morado, Ulrik Gether, John A.G. Briggs, Simon Erlendsson

J Cell Biol (2026) 225 (6): e202503059.

https://doi.org/10.1083/jcb.202503059

Published: 04 May 2026

View article titled, Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy

Journal Articles

Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1

Sophie M. Hurwitz, William N. Zagotta, Sharona E. Gordon, Suzanne Hoppins

J Cell Biol (2026) 225 (7): e202511077.

https://doi.org/10.1083/jcb.202511077

Published: 04 May 2026

View article titled, Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1

Includes: Supplementary data

Journal Articles

Pulling the strings: Contractile VE-cadherin junctions to stabilize angiogenic sprouts

Stephan Huveneers

J Cell Biol (2026) 225 (6): e202603197.

https://doi.org/10.1083/jcb.202603197

Published: 30 April 2026

View article titled, Pulling the strings: Contractile VE-cadherin junctions to stabilize angiogenic sprouts

Journal Articles

The environmental stress response regulates biophysics of the cytoplasm and survival in quiescence

Lorena Kronig, Carmen A. Weber, Pablo Aurelio Gómez-García, Jonas S. Fischer, Christian Doerig, Agnès Michel, Paolo Ronchi, Sarah Khawaja, Paola Picotti, Benoît Kornmann, Karsten Weis

J Cell Biol (2026) 225 (6): e202601119.

https://doi.org/10.1083/jcb.202601119

Published: 30 April 2026

View article titled, The environmental stress response regulates biophysics of the cytoplasm and survival in quiescence

Includes: Supplementary data

Journal Articles

Regulation of the Cell Wall Integrity pathway at the contact site between mating partners in yeast

Erin R. Curtis, Aarshi Jain, Daniel J. Lew

J Cell Biol (2026) 225 (7): e202508068.

https://doi.org/10.1083/jcb.202508068

Published: 30 April 2026

View article titled, Regulation of the Cell Wall Integrity pathway at the contact site between mating partners in yeast

Includes: Supplementary data

Journal Articles

In memoriam: Richard O. Hynes

Douglas W. DeSimone, Sophie Astrof, Martin A. Schwartz

J Cell Biol (2026) 225 (5): e202603201.

https://doi.org/10.1083/jcb.202603201

Published: 28 April 2026

View article titled, In memoriam: Richard O. Hynes

Journal Articles

Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility

Meghan C. Bacher, Julie E. Choe, Jiawen Jiang, Joanna M. Idrovo, Joshua T. Del Mundo, Michal Hammel, Matthew D. Welch

J Cell Biol (2026) 225 (7): e202508117.

https://doi.org/10.1083/jcb.202508117

Published: 28 April 2026

View article titled, Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility

Includes: Supplementary data

Journal Articles

Scrib organizes cortical actomyosin clusters to maintain adherens junctions and angiogenic sprouting

Lakyn N. Mayo, Fiona Duong, Ana Mompeón, Kyle A. Jacobs, M. Luisa Iruela-Arispe, Matthew L. Kutys

J Cell Biol (2026) 225 (6): e202503146.

https://doi.org/10.1083/jcb.202503146

Published: 27 April 2026

View article titled, Scrib organizes cortical actomyosin clusters to maintain adherens junctions and angiogenic sprouting

Includes: Supplementary data

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PI(3)P regulates mitochondrial dynamics through EXC-5–dependent actin remodeling

Chromosome segregation synchrony in S. pombe is noise limited and arises without positive feedback

Eosinophils promote a second wave of postnatal smooth muscle differentiation in intestinal villi

Neutrophil serine proteases degrade endothelial cortactin and promote extravasation

A deep dive into functional ribosome specialization

Mitochondrially tethered Mmm1 can function as a sole lipid transporter at ER–mitochondria contacts

Disruption of macrophage cell volume drives inflammatory responses and type I interferon signaling

Bitesize bundles F-actin and influences actin remodeling in syncytial Drosophila embryo development

NASP functions in the cytoplasm to prevent histone H3 aggregation during early embryogenesis

Phosphatidylserine is a component of the gradient-tracking machine in mating yeast

Optogenetic control of PLC-γ1 activity directs cell motility

LGL-1 and the RhoGAP protein PAC-1 redundantly polarize the Caenorhabditis elegans embryonic epidermis

Ultrastructure of dopaminergic varicosities revealed by cryo-correlative light and electron microscopy

Time-resolved tmFRET reveals GTP-coupled conformational changes in Mfn1

Pulling the strings: Contractile VE-cadherin junctions to stabilize angiogenic sprouts

The environmental stress response regulates biophysics of the cytoplasm and survival in quiescence

Regulation of the Cell Wall Integrity pathway at the contact site between mating partners in yeast

In memoriam: Richard O. Hynes

Divergent Rickettsia species exhibit distinct mechanisms of actin-based motility

Scrib organizes cortical actomyosin clusters to maintain adherens junctions and angiogenic sprouting

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