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Journal Articles

Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem

Alexandre R. Gingras, Frederic Lagarrigue, Monica N. Cuevas, Andrew J. Valadez, Marcus Zorovich, Wilma McLaughlin, Miguel Alejandro Lopez-Ramirez, Nicolas Seban, Klaus Ley, William B. Kiosses, Mark H. Ginsberg

J Cell Biol (2019) 218 (6): 1799–1809.

https://doi.org/10.1083/jcb.201810061

Published: 15 April 2019

View article titled, Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem

Includes: Supplementary data

Journal Articles

Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development

In Special Collection:

Cell Adhesion

Hao Sun, Frederic Lagarrigue, Alexandre R. Gingras, Zhichao Fan, Klaus Ley, Mark H. Ginsberg

J Cell Biol (2018) 217 (4): 1453–1465.

https://doi.org/10.1083/jcb.201707055

Published: 13 March 2018

View article titled, Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development

Includes: Supplementary data

Journal Articles

Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration

Shujie Wang, Takashi Watanabe, Kenji Matsuzawa, Akira Katsumi, Mai Kakeno, Toshinori Matsui, Feng Ye, Kazuhide Sato, Kiyoko Murase, Ikuko Sugiyama, Kazushi Kimura, Akira Mizoguchi, Mark H. Ginsberg, John G. Collard, Kozo Kaibuchi

J Cell Biol (2012) 199 (2): 331–345.

https://doi.org/10.1083/jcb.201202041

Published: 15 October 2012

View article titled, Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration

Includes: Supplementary data

Journal Articles

Structural basis of the junctional anchorage of the cerebral cavernous malformations complex

Alexandre R. Gingras, Jian J. Liu, Mark H. Ginsberg

J Cell Biol (2012) 199 (1): 39–48.

https://doi.org/10.1083/jcb.201205109

Published: 24 September 2012

View article titled, Structural basis of the junctional anchorage of the cerebral cavernous malformations complex

Includes: Multimedia, Supplementary data

Journal Articles

Talin activates integrins by altering the topology of the β transmembrane domain

Chungho Kim, Feng Ye, Xiaohui Hu, Mark H. Ginsberg

J Cell Biol (2012) 197 (5): 605–611.

https://doi.org/10.1083/jcb.201112141

Published: 28 May 2012

View article titled, Talin activates integrins by altering the topology of the β transmembrane domain

Includes: Supplementary data

Journal Articles

Recreation of the terminal events in physiological integrin activation

Feng Ye, Guiqing Hu, Dianne Taylor, Boris Ratnikov, Andrey A. Bobkov, Mark A. McLean, Stephen G. Sligar, Kenneth A. Taylor, Mark H. Ginsberg

J Cell Biol (2010) 188 (1): 157–173.

https://doi.org/10.1083/jcb.200908045

Published: 04 January 2010

View article titled, Recreation of the terminal events in physiological integrin activation

Includes: Supplementary data

Journal Articles

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3

Naohide Watanabe, Laurent Bodin, Manjula Pandey, Matthias Krause, Shaun Coughlin, Vassiliki A. Boussiotis, Mark H. Ginsberg, Sanford J. Shattil

J Cell Biol (2008) 181 (7): 1211–1222.

https://doi.org/10.1083/jcb.200803094

Published: 23 June 2008

View article titled, Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3

Journal Articles

KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell–cell junctions

Angela Glading, Jaewon Han, Rebecca A. Stockton, Mark H. Ginsberg

J Cell Biol (2007) 179 (2): 247–254.

https://doi.org/10.1083/jcb.200705175

Published: 22 October 2007

View article titled, KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell–cell junctions

Includes: Supplementary data

Journal Articles

CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling

Chloé C. Féral, Andries Zijlstra, Eugene Tkachenko, Gerald Prager, Margaret L. Gardel, Marina Slepak, Mark H. Ginsberg

J Cell Biol (2007) 178 (4): 701–711.

https://doi.org/10.1083/jcb.200705090

Published: 06 August 2007

View article titled, CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling

Includes: Supplementary data

Journal Articles

Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

Wei Zou, Hideki Kitaura, Jennifer Reeve, Fanxin Long, Victor L.J. Tybulewicz, Sanford J. Shattil, Mark H. Ginsberg, F. Patrick Ross, Steven L. Teitelbaum

J Cell Biol (2007) 176 (6): 877–888.

https://doi.org/10.1083/jcb.200611083

Published: 12 March 2007

View article titled, Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

Includes: Supplementary data

Journal Articles

RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration

Lawrence E. Goldfinger, Celeste Ptak, Erin D. Jeffery, Jeffrey Shabanowitz, Donald F. Hunt, Mark H. Ginsberg

J Cell Biol (2006) 174 (6): 877–888.

https://doi.org/10.1083/jcb.200603111

Published: 11 September 2006

View article titled, RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration

Journal Articles

α₄β₁-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the α₄-cytoplasmic domain

Ronen Alon, Sara W. Feigelson, Eugenia Manevich, David M. Rose, Julia Schmitz, Darryl R. Overby, Eitan Winter, Valentin Grabovsky, Vera Shinder, Benjamin D. Matthews, Maya Sokolovsky-Eisenberg, Donald E. Ingber, Martin Benoit, Mark H. Ginsberg

J Cell Biol (2005) 171 (6): 1073–1084.

https://doi.org/10.1083/jcb.200503155

Published: 19 December 2005

View article titled, α4β1-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the α4-cytoplasmic domain

Includes: Supplementary data

Journal Articles

Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration

Lawrence E. Goldfinger, Jaewon Han, William B. Kiosses, Alan K. Howe, Mark H. Ginsberg

J Cell Biol (2003) 162 (4): 731–741.

https://doi.org/10.1083/jcb.200304031

Published: 11 August 2003

View article titled, Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration

Includes: Supplementary data

Journal Articles

A Single Immunoglobulin-like Domain of the Human Neural Cell Adhesion Molecule L1 Supports Adhesion by Multiple Vascular and Platelet Integrins

Brunhilde Felding-Habermann, Steve Silletti, Fang Mei, Chi-Hung Siu, Paul M. Yip, Peter C. Brooks, David A. Cheresh, Timothy E. O'Toole, Mark H. Ginsberg, Anthony M.P. Montgomery

J Cell Biol (1997) 139 (6): 1567–1581.

https://doi.org/10.1083/jcb.139.6.1567

Published: 15 December 1997

View article titled, A Single Immunoglobulin-like Domain of the Human Neural Cell Adhesion Molecule L1 Supports Adhesion by Multiple Vascular and Platelet Integrins

Journal Articles

Affinity Modulation of Platelet Integrin α_IIbβ₃ by β₃-Endonexin, a Selective Binding Partner of the β₃ Integrin Cytoplasmic Tail

Hirokazu Kashiwagi, Martin A. Schwartz, Martin Eigenthaler, K.A. Davis, Mark H. Ginsberg, Sanford J. Shattil

J Cell Biol (1997) 137 (6): 1433–1443.

https://doi.org/10.1083/jcb.137.6.1433

Published: 16 June 1997

View article titled, Affinity Modulation of Platelet Integrin αIIbβ3 by β3-Endonexin, a Selective Binding Partner of the β3 Integrin Cytoplasmic Tail

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Rap1 binding and a lipid-dependent helix in talin F1 domain promote integrin activation in tandem

Transmission of integrin β7 transmembrane domain topology enables gut lymphoid tissue development

Tiam1 interaction with the PAR complex promotes talin-mediated Rac1 activation during polarized cell migration

Structural basis of the junctional anchorage of the cerebral cavernous malformations complex

Talin activates integrins by altering the topology of the β transmembrane domain

Recreation of the terminal events in physiological integrin activation

Mechanisms and consequences of agonist-induced talin recruitment to platelet integrin αIIbβ3

KRIT-1/CCM1 is a Rap1 effector that regulates endothelial cell–cell junctions

CD98hc (SLC3A2) participates in fibronectin matrix assembly by mediating integrin signaling

Syk, c-Src, the αvβ3 integrin, and ITAM immunoreceptors, in concert, regulate osteoclastic bone resorption

RLIP76 (RalBP1) is an R-Ras effector that mediates adhesion-dependent Rac activation and cell migration

α₄β₁-dependent adhesion strengthening under mechanical strain is regulated by paxillin association with the α₄-cytoplasmic domain

Spatial restriction of α4 integrin phosphorylation regulates lamellipodial stability and α4β1-dependent cell migration

A Single Immunoglobulin-like Domain of the Human Neural Cell Adhesion Molecule L1 Supports Adhesion by Multiple Vascular and Platelet Integrins

Affinity Modulation of Platelet Integrin α_IIbβ₃ by β₃-Endonexin, a Selective Binding Partner of the β₃ Integrin Cytoplasmic Tail

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