Mechanobiology 2025
This collection examines the mechanical properties and interactions that shape fundamental operations and structures of cells. Beyond essential new insights into the contractile assemblies of actin and myosin or the biophysical properties of kinesins, mechanobiology research published in JCB encompasses diverse mechanical properties of membranes, organelles and other structures within and among cells. In this collection, readers will discover new insights on chromosome size sensing by kinetochores, mechanical resistance at tight junctions, force-exerting focal adhesions formed by T cells, and how nuclei serve as mechanical bumpers. With these works and many others, JCB is proud to serve as an essential outlet for research that advances our physical view of cellular structures and processes.
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Image © 2024 Nguyen et al.

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