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Mechanobiology 2025

This collection examines the mechanical properties and interactions that shape fundamental operations and structures of cells. Beyond essential new insights into the contractile assemblies of actin and myosin or the biophysical properties of kinesins, mechanobiology research published in JCB encompasses diverse mechanical properties of membranes, organelles and other structures within and among cells. In this collection, readers will discover new insights on chromosome size sensing by kinetochores, mechanical resistance at tight junctions, force-exerting focal adhesions formed by T cells, and how nuclei serve as mechanical bumpers. With these works and many others, JCB is proud to serve as an essential outlet for research that advances our physical view of cellular structures and processes.

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Image © 2024 Nguyen et al.

Special Collection Image
Ryota Orii; Hirokazu Tanimoto
Joshua D. Larson; Natalie A. Heitkamp; Lucas E. Murray; Andrew R. Popchock; Sue Biggins; Charles L. Asbury
Noah F. de Leeuw; Rashmi Budhathoki; Liam J. Russell; Dinah Loerke; J. Todd Blankenship
Chuying Zhou; You Kure Wu; Fumiyoshi Ishidate; Takahiro K. Fujiwara; Mineko Kengaku
Alexia Caillier; David Oleksyn; Deborah J. Fowell; Jim Miller; Patrick W. Oakes
Megan K. Chong; Miquel Rosas-Salvans; Vanna Tran; Sophie Dumont
Bruno A. Cisterna; Kristen Skruber; Makenzie L. Jane; Caleb I. Camesi; Ivan D. Nguyen; Tatiana M. Liu; Peyton V. Warp; Joseph B. Black; Mitchell T. Butler; James E. Bear; Danielle E. Mor; Tracy-Ann Read; Eric A. Vitriol
Xiaorong Pan; Yiqing Hu; Gaowei Lei; Yaxuan Wei; Jie Li; Tongshu Luan; Yunfan Zhang; Yuanyuan Chu; Yu Feng; Wenrong Zhan; Chunxia Zhao; Frédéric A. Meunier; Yifan Liu; Yi Li; Tong Wang
Thanh Phuong Nguyen; Tetsuhisa Otani; Motosuke Tsutsumi; Noriyuki Kinoshita; Sachiko Fujiwara; Tomomi Nemoto; Toshihiko Fujimori; Mikio Furuse
Jahnavi Chikireddy; Léana Lengagne; Rémi Le Borgne; Catherine Durieu; Hugo Wioland; Guillaume Romet-Lemonne; Antoine Jégou
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