Nuclear Organization and Function 2018

Thanks to recent developments in advanced microscopy and sequencing technologies, research at the interface of chromatin biology and epigenetics, nuclear organization, and chromosome architecture has expanded considerably and provided exciting insight into three-dimensional genome dynamics and functions. In this special collection, JCB Editorial Board Member Ana Pombo and Senior Scientific Editor Melina Casadio selected some of JCB's most highly read recent content exploring chromatin structure and how it relates to gene expression and genome functions such as DNA replication and repair. This collection sheds light on genome organization and chromosome conformation, chromatin partners and dynamics during development and disease, and how emerging imaging technologies advance the field. We hope you enjoy this collection and look forward to your feedback on Facebook and Twitter.

Image © 2018 Walther et al.

KEYWORDS

DNA replication, genome organization, Nucleus, histone, telomeres, chromatin, RNA, mechanotransduction, IncRNA, DNA repair, DNA damage, Fanconi anemia, retrotransposon, splicing, DNA, condensin, miRNA, enhancer, epigenetics