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Cell Biology of Infection and the Immune Response 2018

Microbial pathogens have evolved diverse strategies to ensure their survival and replication, while host cells have complex mechanisms to detect infection and neutralize invaders. Understanding how cells mount an effective and measured immune response and the complex interactions between host and pathogens - for viruses, bacteria, and other microbes to evade the host's immune response and for the host to detect, target, and eliminate the infection - is essential to understand the basis of various human diseases and develop appropriate treatments.

In this special collection, JCB Board member Craig Roy and Senior Scientific Editor Melina Casadio explore recent exciting JCB articles that delve into the cell biology and immunobiology of host/pathogen interactions. These papers include some of our most downloaded articles about the mechanisms of pathogen invasion and replication, innate immune signaling, and the determinants of the adaptive immune response. We hope you'll enjoy this collection and look forward to your feedback on social media. Image courtesy of Leptin et al. See: Dynamics of in vivo ASC speck formation.


virus, Immunology, pathogen, immune response, bacteria, cancer, infection, microbiology, inflammation

Special Collection Image
Elias Cornejo; Philipp Schlaermann; Shaeri Mukherjee
DOI: 10.1083/jcb.201701095
Trinna L. Cuellar; Anna-Maria Herzner; Xiaotian Zhang; Yogesh Goyal; Colin Watanabe; Brad A. Friedman; Vasantharajan Janakiraman; Steffen Durinck; Jeremy Stinson; David Arnott; Tommy K. Cheung; Subhra Chaudhuri; Zora Modrusan; Jonas Martin Doerr; Marie Classon; Benjamin Haley
DOI: 10.1083/jcb.201612160
Paola Kuri; Nicole L. Schieber; Thomas Thumberger; Joachim Wittbrodt; Yannick Schwab; Maria Leptin
DOI: 10.1083/jcb.201703103
Sang Bum Kim; Hye Rim Kim; Min Chul Park; Seongmin Cho; Peter C. Goughnour; Daeyoung Han; Ina Yoon; YounHa Kim; Taehee Kang; Eunjoo Song; Pilhan Kim; Hyosun Choi; Ji Young Mun; Chihong Song; Sangmin Lee; Hyun Suk Jung; Sunghoon Kim
DOI: 10.1083/jcb.201605118
Suvagata Roy Chowdhury; Anastasija Reimer; Malvika Sharan; Vera Kozjak-Pavlovic; Ana Eulalio; Bhupesh K. Prusty; Martin Fraunholz; Karthika Karunakaran; Thomas Rudel
DOI: 10.1083/jcb.201608063
Filipa B. Lopes; Štefan Bálint; Salvatore Valvo; James H. Felce; Edith M. Hessel; Michael L. Dustin; Daniel M. Davis
DOI: 10.1083/jcb.201608094
Thomas R. Lerner; Sophie Borel; Daniel J. Greenwood; Urska Repnik; Matthew R.G. Russell; Susanne Herbst; Martin L. Jones; Lucy M. Collinson; Gareth Griffiths; Maximiliano G. Gutierrez
DOI: 10.1083/jcb.201603040
Reed M. O’Connor; Elizabeth F. Stone; Charlotte R. Wayne; Emily V. Marcinkevicius; Matt Ulgherait; Rebecca Delventhal; Meghan M. Pantalia; Vanessa M. Hill; Clarice G. Zhou; Sophie McAllister; Anna Chen; Jennifer S. Ziegenfuss; Wesley B. Grueber; Julie C. Canman; Mimi M. Shirasu-Hiza
DOI: 10.1083/jcb.201607093
Bryan Vander Lugt; Jeremy Riddell; Aly A. Khan; Jason A. Hackney; Justin Lesch; Jason DeVoss; Matthew T. Weirauch; Harinder Singh; Ira Mellman
DOI: 10.1083/jcb.201512012
Katelyn M. Spillane; Pavel Tolar
DOI: 10.1083/jcb.201607064
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