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Centrosomes and Cilia 2018

Centrosomes are major microtubule organizing centers, and cilia are microtubule-based organelles functioning in cell motility and sensory signaling. Recently, important progress has been made to understand the organization and function of these structures of the microtubule cytoskeleton as well as their involvement in cancer, developmental and degenerative disorders, and their connections to cell cycle regulation and differentiation. JCB Editorial Board member Mónica Bettencourt Dias and Senior Scientific Editor Melina Casadio assembled a collection of recent JCB papers advancing our knowledge about cilium and centrosome function in health and disease using diverse experimental systems and model organisms. The selection includes our most highly read articles about the regulation of centriole and centrosome organization and cycle, cilium structure, function, signaling and trafficking, ciliogenesis, and the roles of cilia and centrosomes in cancer and developmental disorders. We hope you enjoy this collection and look forward to your feedback on Facebook and Twitter.

Image © 2018 Serwas et al.

Special Collection Image
Article
Nycole A. Maza; William E. Schiesser; Peter D. Calvert
DOI: 10.1083/jcb.201906024
Report
Jingjing Chen; Jennifer M. Gardner; Zulin Yu; Sarah E. Smith; Sean McKinney; Brian D. Slaughter; Jay R. Unruh; Sue L. Jaspersen
DOI: 10.1083/jcb.201809045
Report
Jérémy Sallé; Jing Xie; Dmitry Ershov; Milan Lacassin; Serge Dmitrieff; Nicolas Minc
DOI: 10.1083/jcb.201807102
Article
Luís Pedro Resende; Augusta Monteiro; Rita Brás; Tatiana Lopes; Claudio E. Sunkel
DOI: 10.1083/jcb.201804205
Review
Zsolt G. Venkei; Yukiko M. Yamashita
DOI: 10.1083/jcb.201807037
Article
Panagiota Louka; Krishna Kumar Vasudevan; Mayukh Guha; Ewa Joachimiak; Dorota Wloga; Raphaël F.-X. Tomasi; Charles N. Baroud; Pascale Dupuis-Williams; Domenico F. Galati; Chad G. Pearson; Luke M. Rice; James J. Moresco; John R. Yates, III; Yu-Yang Jiang; Karl Lechtreck; William Dentler; Jacek Gaertig
DOI: 10.1083/jcb.201804141
Article
Sungsu Lee; Han Yen Tan; Ivayla I. Geneva; Aleksandr Kruglov; Peter D. Calvert
DOI: 10.1083/jcb.201711104
Article
Lai Kuan Dionne; Kyuhwan Shim; Masato Hoshi; Tao Cheng; Jinzhi Wang; Veronique Marthiens; Amanda Knoten; Renata Basto; Sanjay Jain; Moe R. Mahjoub
DOI: 10.1083/jcb.201710019
Article
Tina L. Sing; Minnie P. Hung; Shinsuke Ohnuki; Godai Suzuki; Bryan-Joseph San Luis; Melainia McClain; Jay R. Unruh; Zulin Yu; Jiongwen Ou; Jesse Marshall-Sheppard; Won-Ki Huh; Michael Costanzo; Charles Boone; Yoshikazu Ohya; Sue L. Jaspersen; Grant W. Brown
DOI: 10.1083/jcb.201709009
Report
Carla A.M. Lopes; Carla A.M. Lopes; Marta Mesquita; Ana Isabel Cunha; Joana Cardoso; Sara Carapeta; Cátia Laranjeira; António E. Pinto; José B. Pereira-Leal; António Dias-Pereira; Mónica Bettencourt-Dias; Mónica Bettencourt-Dias; Paula Chaves; Paula Chaves
DOI: 10.1083/jcb.201711191
Article
Kan Yaguchi; Takahiro Yamamoto; Ryo Matsui; Yuki Tsukada; Atsuko Shibanuma; Keiko Kamimura; Toshiaki Koda; Ryota Uehara
DOI: 10.1083/jcb.201701151
Spotlight
Simon Gemble; Renata Basto
DOI: 10.1083/jcb.201802084
Article
Mustafa G. Aydogan; Alan Wainman; Saroj Saurya; Thomas L. Steinacker; Anna Caballe; Zsofia A. Novak; Janina Baumbach; Nadine Muschalik; Jordan W. Raff
DOI: 10.1083/jcb.201801014
Report
Anne-Clémence Vion; Silvanus Alt; Alexandra Klaus-Bergmann; Anna Szymborska; Tuyu Zheng; Tijana Perovic; Adel Hammoutene; Marta Bastos Oliveira; Eireen Bartels-Klein; Irene Hollfinger; Pierre-Emmanuel Rautou; Miguel O. Bernabeu; Holger Gerhardt
DOI: 10.1083/jcb.201706151
Article
Fan Ye; Andrew R. Nager; Maxence V. Nachury
DOI: 10.1083/jcb.201709041
Article
Wanlu Zhang; Annett Neuner; Diana Rüthnick; Timo Sachsenheimer; Christian Lüchtenborg; Britta Brügger; Elmar Schiebel
DOI: 10.1083/jcb.201706024
Review
Jadranka Loncarek; Mónica Bettencourt-Dias
DOI: 10.1083/jcb.201704093
Spotlight
Diana Vargas-Hurtado; Renata Basto
DOI: 10.1083/jcb.201712033
Report
Fabian Marc Schmid; Kenneth Bødtker Schou; Martin Juel Vilhelm; Maria Schrøder Holm; Loretta Breslin; Pietro Farinelli; Lars Allan Larsen; Jens Skorstengaard Andersen; Lotte Bang Pedersen; Søren Tvorup Christensen
DOI: 10.1083/jcb.201611050
Article
Alexander D. Rhys; Pedro Monteiro; Christopher Smith; Malti Vaghela; Teresa Arnandis; Takuya Kato; Birgit Leitinger; Erik Sahai; Andrew McAinsh; Guillaume Charras; Susana A. Godinho
DOI: 10.1083/jcb.201704102
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