Lanthanum staining of embryonic chick cell reaggregates reveals an intercellular material composed of fibrils. Fibrillar arrays may be composed of parallel fibrils with a 35 A center-to-center spacing. Fibrils may also be disoriented, long, and tortuous. Newly dissociated cells show little lanthanum staining surface material, but appreciable amounts are present after 6 hr of reaggregation. Examination of intact tissue does not give the same clear evidence of a fibrillar matrix surrounding the cells, but treatment with a number of agents permits observation of intercellular fibrils, and in some cases there is evidence of orientation. Thus fibrillar material must be taken into account in considering mechanisms of cell aggregation.
Article| January 01 1969
A FIBRILLAR INTERCELLULAR MATERIAL BETWEEN REAGGREGATING EMBRYONIC CHICK CELLS
From the Whitman Laboratory, the University of Chicago, Chicago, Illinois 60637
Received: May 20 1968
Revision Received: August 19 1968
Online ISSN: 1540-8140
Print ISSN: 0021-9525
Copyright © 1969 by The Rockefeller University Press.
Jane Overton; A FIBRILLAR INTERCELLULAR MATERIAL BETWEEN REAGGREGATING EMBRYONIC CHICK CELLS . J Cell Biol 1 January 1969; 40 (1): 136–143. doi: https://doi.org/10.1083/jcb.40.1.136
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