In Caenorhabditis elegans embryos, early blastomeres of the P cell lineage divide successively on the same axis. This axis is a consequence of the specific rotational movement of the pair of centrosomes and nucleus (Hyman, A. A., and J. G. White. 1987. J. Cell Biol. 105:2123-2135). A laser has been used to perturb the centrosome movements that determine the pattern of early embryonic divisions. The results support a previously proposed model in which a centrosome rotates towards its correct position by shortening of connections, possibly microtubules, between a centrosome and a defined site on the cortex of the embryo.
Article| September 01 1989
Centrosome movement in the early divisions of Caenorhabditis elegans: a cortical site determining centrosome position.
A A Hyman
Laboratory of Molecular Biology, Medical Research Council, Cambridge, England.
Online Issn: 1540-8140
Print Issn: 0021-9525
J Cell Biol (1989) 109 (3): 1185–1193.
- Views Icon Views
- Share Icon Share
- Search Site
A A Hyman; Centrosome movement in the early divisions of Caenorhabditis elegans: a cortical site determining centrosome position.. J Cell Biol 1 September 1989; 109 (3): 1185–1193. doi: https://doi.org/10.1083/jcb.109.3.1185
Download citation file: