When few RGCs are around, radial division (shown) can be converted to cirumferential.
Retinal ganglion cell (RGC) formation is dependent on Ath5. Using time-lapse microscopy, the team found that as cells began to express Ath5 they migrated toward the outer surface of the cup-shaped retina. Once there, the cells divided one time, with the plane of their spindle oriented along the radial axis of the retina (i.e., perpendicular to the sheet). One daughter cell migrated back toward the center of the retina and became an RGC, while the other remained near...
The Rockefeller University Press
2005
The Rockefeller University Press
2005
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