Proteins enter chloroplasts through a four-channeled translocon.
Previous work identified four proteins important for translocation across the outer chloroplast membrane, but the architecture of the translocon remained unknown. In the new work, the authors purified a core complex containing the translocon proteins Toc75, Toc34, and a fragment of Toc159, and found that this complex can recognize and translocate chloroplast precursor proteins. The absence of Toc64 in the functional complex suggests that this protein only transiently associates with the core translocon. Electron microscopy and image analysis reveals that the core complex has a toroidal shape, with a finger-like domain dividing a...
The Rockefeller University Press
2003
The Rockefeller University Press
2003
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