ROCK-steady centriole migration

Centriole migration to the midbody during cytokinesis initiates exit from mitosis and the final separation of dividing cells. New results by Chevrier et al. on page 807 indicate that this migration is dependent on a Rho-associated kinase in a process that may link two distinct events in cytokinesis.

Both the mother and daughter centrosomes are made up of a centriole and the surrounding pericentriolar matrix (PCM). The mother centriole is normally rather immobile, remaining near the cell center throughout most of the cell cycle. In late telophase, however, the mother centriole migrates to the cytoplasmic bridge tethering the daughter cells, signaling the end of mitosis and separation of the cells. Upon exit from mitosis, the mother centriole again returns to a nearly immobile state near the cell center.

This behavior of the mother centriole at...