FGF-4 binds lung (bottom) but not heart (top), whereas FGF-2 binds both.
The formation of an FGF signaling complex requires that both an FGF-family protein and its receptor interact with a heparan sulfate proteoglycan, but little was known about the function of heparan sulfate in this complex. The authors probed frozen tissue sections of mouse embryos with FGF-2...
The Rockefeller University Press
2001
The Rockefeller University Press
2001
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