Sodium channels (white) cluster at nodes of Ranvier.
The interaction of the β subunits with neurofascin, long known to be a cell adhesion molecule in neurons, did not come entirely as a surprise, since β subunits show sequence homology to cell adhesion molecules. This paper provides new evidence that the β subunits of sodium channels perform a dual role: anchoring the sodium channel through lateral interactions in the plasma membrane, as well as their known function of speeding up the opening and closing of sodium channels....
The Rockefeller University Press
2001
The Rockefeller University Press
2001
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