FtsZ forms the cytoskeletal framework of the cytokinetic ring in bacteria, and appears to play the major role in constriction of the furrow at septation. Until recently, FtsZ had been found in every eubacterium and archaebacterium, and was thought to be the major and essential component of the division machine (Erickson 1997). FtsZ has also been found in chloroplasts (Osteryoung et al. 1998), which was expected since these plastids originated from bacterial ancestors. An apparent missing link was that FtsZ was absent from mitochondria, which are also of prokaryotic origin. There is no FtsZ in the completed genomes of Saccharomyces cerevisiae and Caenorhabditis elegans, and none in the extensive EST databases from human and animals. Now the mystery of mitochondrial cell division seems well on its way to resolution: most mitochondria have replaced FtsZ...
Skip Nav Destination
Article navigation
20 March 2000
Review|
March 20 2000
Dynamin and Ftsz: Missing Links in Mitochondrial and Bacterial Division
Harold P. Erickson
Harold P. Erickson
aDepartment of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710
Search for other works by this author on:
Harold P. Erickson
aDepartment of Cell Biology, Duke University Medical Center, Durham, North Carolina 27710
Received:
February 08 2000
Accepted:
February 18 2000
Online ISSN: 1540-8140
Print ISSN: 0021-9525
© 2000 The Rockefeller University Press
2000
The Rockefeller University Press
J Cell Biol (2000) 148 (6): 1103–1106.
Article history
Received:
February 08 2000
Accepted:
February 18 2000
Citation
Harold P. Erickson; Dynamin and Ftsz: Missing Links in Mitochondrial and Bacterial Division. J Cell Biol 20 March 2000; 148 (6): 1103–1106. doi: https://doi.org/10.1083/jcb.148.6.1103
Download citation file:
Sign in
Don't already have an account? Register
Client Account
You could not be signed in. Please check your email address / username and password and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your InstitutionEmail alerts
Advertisement
Advertisement