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Journal Articles

Phosphorylation-dependent regional motility of the ciliary kinesin OSM-3

Peng Huang, Guanghan Chen, Zhiwen Zhu, Shimin Wang, Zhe Chen, Yongping Chai, Wei Li, Guangshuo Ou
Journal: Journal of Cell Biology
J Cell Biol (2025) 224 (7): e202407152.
https://doi.org/10.1083/jcb.202407152
Published: 24 April 2025
View article titled, Phosphorylation-dependent regional motility of the ciliary kinesin OSM-3
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Includes: Supplementary data
Journal Articles

PTPN23-dependent activation of PI3KC2α is a therapeutic vulnerability of BRAF-mutant cancers

Ying He, Wei Li, Meiling Zhang, Hui Wang, Peilu Lin, Ying Yu, Bin Huang, Meng Hao, Jianuo He, Weiyao Kong, Dan Luo, Tengteng Xu, Jiaqi Wang, Ying Huang, Qinwen Zhao, Ying Liu, Jie Zhang, Yong Nian, Lei Zhang, Bo Zhu, Chengqian Yin
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (3): e20241147.
https://doi.org/10.1084/jem.20241147
Published: 22 January 2025
View article titled, PTPN23-dependent activation of PI3KC2α is a therapeutic vulnerability of BRAF-mutant cancers
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Includes: Supplementary data
Journal Articles

BLK positively regulates TLR/IL-1R signaling by catalyzing TOLLIP phosphorylation

Wei-Wei Li, Xu-Xu Fan, Zhi-Sheng Xu, Zi-Xiang Zhu, Zhao-Yu Zhu, Xue-Jing Cao, Dan-Shi Pei, Yi-Zhuo Wang, Ji-Yan Zhang, Yan-Yi Wang, Hai-Xue Zheng
Journal: Journal of Cell Biology
J Cell Biol (2023) 223 (2): e202302081.
https://doi.org/10.1083/jcb.202302081
Published: 11 December 2023
View article titled, BLK positively regulates TLR/IL-1R signaling by catalyzing TOLLIP phosphorylation
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Includes: Supplementary data
Journal Articles

A dysregulated sebum–microbial metabolite–IL-33 axis initiates skin inflammation in atopic dermatitis

In Special Collection:
Fibrosis Collection 2023 , Microbiota, Diet, Metabolites and the Immune System 2023
Zhuoqiong Qiu, Zhenlai Zhu, Xiaochun Liu, Baichao Chen, Huibin Yin, Chaoying Gu, Xiaokai Fang, Ronghui Zhu, Tianze Yu, Wenli Mi, Hong Zhou, Yufeng Zhou, Xu Yao, Wei Li
Journal: Journal of Experimental Medicine
J Exp Med (2022) 219 (10): e20212397.
https://doi.org/10.1084/jem.20212397
Published: 16 August 2022
View article titled, A dysregulated sebum–microbial metabolite–IL-33 axis initiates skin inflammation in atopic dermatitis
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Includes: Supplementary data
Journal Articles

SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity

In Special Collection:
The Year in Cell Biology: 2022
Liying Wang, Chao Liu, Bo Yang, Haotian Zhang, Jian Jiao, Ruidan Zhang, Shujun Liu, Sai Xiao, Yinghong Chen, Bo Liu, Yanjie Ma, Xuefeng Duan, Yueshuai Guo, Mengmeng Guo, Bingbing Wu, Xiangdong Wang, Xingxu Huang, Haitao Yang, Yaoting Gui, Min Fang, Luo Zhang, Shuguang Duo, Xuejiang Guo, Wei Li
Journal: Journal of Cell Biology
J Cell Biol (2022) 221 (7): e202108015.
https://doi.org/10.1083/jcb.202108015
Published: 08 June 2022
View article titled, SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2ZYG11B activity
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Includes: Supplementary data
Journal Articles

Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture

Yichen Wang, Lin Jia, Cong Wang, Zhonghua Du, Shilin Zhang, Lei Zhou, Xue Wen, Hui Li, Huiling Chen, Yuanyuan Nie, Dan Li, Shanshan Liu, Daniela Salgado Figueroa, Ferhat Ay, Wei Xu, Songling Zhang, Wei Li, Jiuwei Cui, Andrew R. Hoffman, Hui Guo, Ji-Fan Hu
Journal: Journal of Cell Biology
J Cell Biol (2022) 221 (4): e202009134.
https://doi.org/10.1083/jcb.202009134
Published: 16 February 2022
View article titled, Pluripotency exit is guided by the Peln1-mediated disruption of intrachromosomal architecture
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Includes: Supplementary data
Journal Articles

Genome-wide mutational signatures revealed distinct developmental paths for human B cell lymphomas

In Special Collection:
2022 Clinical Collection on Cancer , JEM Hematologic Malignancies Collection 2021
Xiaofei Ye, Weicheng Ren, Dongbing Liu, Xiaobo Li, Wei Li, Xianhuo Wang, Fei-Long Meng, Leng-Siew Yeap, Yong Hou, Shida Zhu, Rafael Casellas, Huilai Zhang, Kui Wu, Qiang Pan-Hammarström
Journal: Journal of Experimental Medicine
J Exp Med (2020) 218 (2): e20200573.
https://doi.org/10.1084/jem.20200573
Published: 02 November 2020
View article titled, Genome-wide mutational signatures revealed distinct developmental paths for human B cell lymphomas
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Includes: Supplementary data
Journal Articles

Radial contractility of actomyosin rings facilitates axonal trafficking and structural stability

In Special Collection:
Cellular Neurobiology 2020 , Mechanobiology 2022
Tong Wang, Wei Li, Sally Martin, Andreas Papadopulos, Merja Joensuu, Chunxia Liu, Anmin Jiang, Golnoosh Shamsollahi, Rumelo Amor, Vanessa Lanoue, Pranesh Padmanabhan, Frédéric A. Meunier
Journal: Journal of Cell Biology
J Cell Biol (2020) 219 (5): e201902001.
https://doi.org/10.1083/jcb.201902001
Published: 17 March 2020
View article titled, Radial contractility of actomyosin rings facilitates axonal trafficking and structural stability
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Journal Articles

Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I

In Special Collection:
Chromosome Organization and Segregation
Yufei Li, Leyun Wang, Linlin Zhang, Zhengquan He, Guihai Feng, Hao Sun, Jiaqiang Wang, Zhikun Li, Chao Liu, Jiabao Han, Junjie Mao, Pengcheng Li, Xuewei Yuan, Liyuan Jiang, Ying Zhang, Qi Zhou, Wei Li
Journal: Journal of Cell Biology
J Cell Biol (2019) 218 (5): 1553–1563.
https://doi.org/10.1083/jcb.201808088
Published: 15 February 2019
View article titled, Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I
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Includes: Supplementary data
Journal Articles

Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells

Fengyi Gao, Guoping Li, Chao Liu, Hui Gao, Hao Wang, Weixiao Liu, Min Chen, Yongliang Shang, Lina Wang, Jian Shi, Wenlong Xia, Jianwei Jiao, Fei Gao, Jian Li, Liang Chen, Wei Li
Journal: Journal of Cell Biology
J Cell Biol (2018) 217 (6): 2103–2119.
https://doi.org/10.1083/jcb.201710078
Published: 04 April 2018
View article titled, Autophagy regulates testosterone synthesis by facilitating cholesterol uptake in Leydig cells
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Includes: Supplementary data
Journal Articles

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function

Philip D. Kiser, Jianye Zhang, Aditya Sharma, Juan M. Angueyra, Alexander V. Kolesnikov, Mohsen Badiee, Gregory P. Tochtrop, Junzo Kinoshita, Neal S. Peachey, Wei Li, Vladimir J. Kefalov, Krzysztof Palczewski
Journal: Journal of General Physiology
J Gen Physiol (2018) 150 (4): 571–590.
https://doi.org/10.1085/jgp.201711815
Published: 02 March 2018
View article titled, Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function
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Includes: Supplementary data
Journal Articles

Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy

In Special Collection:
Vascular Biology and Human Disease , Bioenergetics and Metabolic Diseases
Michelle E. LeBlanc, Weiwen Wang, Xiuping Chen, Nora B. Caberoy, Feiye Guo, Chen Shen, Yanli Ji, Hong Tian, Hui Wang, Rui Chen, Wei Li
Journal: Journal of Experimental Medicine
J Exp Med (2017) 214 (4): 1029–1047.
https://doi.org/10.1084/jem.20161802
Published: 22 March 2017
View article titled, Secretogranin III as a disease-associated ligand for antiangiogenic therapy of diabetic retinopathy
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Includes: Supplementary data
Journal Articles

Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus

He Zhang, Michael J. Zeitz, Hong Wang, Beibei Niu, Shengfang Ge, Wei Li, Jiuwei Cui, Guanjun Wang, Guanxiang Qian, Michael J. Higgins, Xianqun Fan, Andrew R. Hoffman, Ji-Fan Hu
Journal: Journal of Cell Biology
J Cell Biol (2014) 204 (1): 61–75.
https://doi.org/10.1083/jcb.201304152
Published: 06 January 2014
View article titled, Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus
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Includes: Supplementary data
Journal Articles

Plasma glutamate–modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury–induced acute lung injury

Shuang-Shuang Dai, Hao Wang, Nan Yang, Jian-Hong An, Wei Li, Ya-Lei Ning, Pei-Fang Zhu, Jiang-Fan Chen, Yuan-Guo Zhou
Journal: Journal of Experimental Medicine
J Exp Med (2013) 210 (4): 839–851.
https://doi.org/10.1084/jem.20122196
Published: 11 March 2013
View article titled, Plasma glutamate–modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury–induced acute lung injury
Open the PDF for Plasma glutamate–modulated interaction of A2AR and mGluR5 on BMDCs aggravates traumatic brain injury–induced acute lung injury in another window
Includes: Supplementary data
Journal Articles

Apoptotic regulators promote cytokinetic midbody degradation in C. elegans

Yongping Chai, Dong Tian, Yihong Yang, Guoxin Feng, Ze Cheng, Wei Li, Guangshuo Ou
Journal: Journal of Cell Biology
J Cell Biol (2012) 199 (7): 1047–1055.
https://doi.org/10.1083/jcb.201209050
Published: 17 December 2012
View article titled, Apoptotic regulators promote cytokinetic midbody degradation in C. elegans
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Includes: Multimedia, Supplementary data
Journal Articles

Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell

Wei Li, Wei Zou, Yihong Yang, Yongping Chai, Baohui Chen, Shiya Cheng, Dong Tian, Xiaochen Wang, Ronald D. Vale, Guangshuo Ou
Journal: Journal of Cell Biology
J Cell Biol (2012) 197 (1): 27–35.
https://doi.org/10.1083/jcb.201111053
Published: 26 March 2012
View article titled, Autophagy genes function sequentially to promote apoptotic cell corpse degradation in the engulfing cell
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Includes: Supplementary data
Journal Articles

A novel neuroprotective therapy for Parkinson’s disease using a viral noncoding RNA that protects mitochondrial Complex I activity

Wei-Li Kuan, Emma Poole, Michael Fletcher, Sharon Karniely, Pam Tyers, Mark Wills, Roger A. Barker, John H. Sinclair
Journal: Journal of Experimental Medicine
J Exp Med (2011) 209 (1): 1–10.
https://doi.org/10.1084/jem.20111126
Published: 19 December 2011
View article titled, A novel neuroprotective therapy for Parkinson’s disease using a viral noncoding RNA that protects mitochondrial Complex I activity
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Journal Articles

CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses

Jing Zhou, Paul C.Y. Tang, Lingfeng Qin, Peter M. Gayed, Wei Li, Eleni A. Skokos, Themis R. Kyriakides, Jordan S. Pober, George Tellides
Journal: Journal of Experimental Medicine
J Exp Med (2010) 207 (9): 1951–1966.
https://doi.org/10.1084/jem.20100098
Published: 23 August 2010
View article titled, CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses
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Includes: Supplementary data
Journal Articles

An eIF4E-binding protein regulates katanin protein levels in C. elegans embryos

Wei Li, Leah R. DeBella, Tugba Guven-Ozkan, Rueyling Lin, Lesilee S. Rose
Journal: Journal of Cell Biology
J Cell Biol (2009) 187 (1): 33–42.
https://doi.org/10.1083/jcb.200903003
Published: 28 September 2009
View article titled, An eIF4E-binding protein regulates katanin protein levels in C. elegans embryos
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Includes: Supplementary data
Journal Articles

DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release

Xiao-Wei Chen, Ya-Qin Feng, Chan-Juan Hao, Xiao-Li Guo, Xin He, Zhi-Yong Zhou, Ning Guo, Hong-Ping Huang, Wei Xiong, Hui Zheng, Pan-Li Zuo, Claire Xi Zhang, Wei Li, Zhuan Zhou
Journal: Journal of Cell Biology
J Cell Biol (2008) 181 (5): 791–801.
https://doi.org/10.1083/jcb.200711021
Published: 26 May 2008
View article titled, DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release
Open the PDF for DTNBP1, a schizophrenia susceptibility gene, affects kinetics of transmitter release in another window
Includes: Multimedia, Supplementary data