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Manuel Covarrubias
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Journal Articles

Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation

Elaine Yang, Daniele Granata, Roderic G. Eckenhoff, Vincenzo Carnevale, Manuel Covarrubias
Journal: Journal of General Physiology
J Gen Physiol (2018) 150 (9): 1299–1316.
https://doi.org/10.1085/jgp.201711924
Published: 17 July 2018
View articletitled, Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation
Open the PDF for Propofol inhibits prokaryotic voltage-gated Na+ channels by promoting activation-coupled inactivation in another window
Includes: Supplementary data
Journal Articles

Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites

Yali Wang, Elaine Yang, Marta M. Wells, Vasyl Bondarenko, Kellie Woll, Vincenzo Carnevale, Daniele Granata, Michael L. Klein, Roderic G. Eckenhoff, William P. Dailey, Manuel Covarrubias, Pei Tang, Yan Xu
Journal: Journal of General Physiology
J Gen Physiol (2018) 150 (9): 1317–1331.
https://doi.org/10.1085/jgp.201811993
Published: 17 July 2018
View articletitled, Propofol inhibits the voltage-gated sodium channel NaChBac at multiple sites
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Includes: Supplementary data
Journal Articles

Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels

Jeffrey D. Fineberg, David M. Ritter, Manuel Covarrubias
Journal: Journal of General Physiology
J Gen Physiol (2012) 140 (5): 513–527.
https://doi.org/10.1085/jgp.201210869
Published: 29 October 2012
View articletitled, Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels
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Includes: Supplementary data
Journal Articles

Gating Charge Immobilization in Kv4.2 Channels: The Basis of Closed-State Inactivation

Kevin Dougherty, Jose A. De Santiago-Castillo, Manuel Covarrubias
Journal: Journal of General Physiology
J Gen Physiol (2008) 131 (3): 257–273.
https://doi.org/10.1085/jgp.200709938
Published: 25 February 2008
View articletitled, Gating Charge Immobilization in Kv4.2 Channels: The Basis of Closed-State Inactivation
Open the PDF for Gating Charge Immobilization in Kv4.2 Channels: The Basis of Closed-State Inactivation in another window
Includes: Supplementary data
Journal Articles

A Dipeptidyl Aminopeptidase–like Protein Remodels Gating Charge Dynamics in Kv4.2 Channels

Kevin Dougherty, Manuel Covarrubias
Journal: Journal of General Physiology
J Gen Physiol (2006) 128 (6): 745–753.
https://doi.org/10.1085/jgp.200609668
Published: 27 November 2006
View articletitled, A Dipeptidyl Aminopeptidase–like Protein Remodels Gating Charge Dynamics in Kv4.2 Channels
Open the PDF for A Dipeptidyl Aminopeptidase–like Protein Remodels Gating Charge Dynamics in Kv4.2 Channels in another window
Includes: Supplementary data
Journal Articles

Voltage-dependent Gating Rearrangements in the Intracellular T1–T1 Interface of a K+ Channel

Guangyu Wang, Manuel Covarrubias
Journal: Journal of General Physiology
J Gen Physiol (2006) 127 (4): 391–400.
https://doi.org/10.1085/jgp.200509442
Published: 13 March 2006
View articletitled, Voltage-dependent Gating Rearrangements in the Intracellular T1–T1 Interface of a K+ Channel
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Includes: Supplementary data
Journal Articles

Functionally Active T1-T1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv4 Channels

Guangyu Wang, Mohammad Shahidullah, Carmen A. Rocha, Candace Strang, Paul J. Pfaffinger, Manuel Covarrubias
Journal: Journal of General Physiology
J Gen Physiol (2005) 126 (1): 55–69.
https://doi.org/10.1085/jgp.200509288
Published: 13 June 2005
View articletitled, Functionally Active T1-T1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv4 Channels
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Journal Articles

Inactivation Gating of Kv4 Potassium Channels : Molecular Interactions Involving the Inner Vestibule of the Pore

Henry H. Jerng, Mohammad Shahidullah, Manuel Covarrubias
Journal: Journal of General Physiology
J Gen Physiol (1999) 113 (5): 641–660.
https://doi.org/10.1085/jgp.113.5.641
Published: 01 May 1999
View articletitled, Inactivation Gating of Kv4 Potassium Channels : Molecular Interactions Involving the Inner Vestibule of the Pore
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Journal Articles

Interactions between Multiple Phosphorylation Sites in the Inactivation Particle of a K+ Channel : Insights into the Molecular Mechanism of Protein Kinase C Action

Edward J. Beck, Roger G. Sorensen, Simon J. Slater, Manuel Covarrubias
Journal: Journal of General Physiology
J Gen Physiol (1998) 112 (1): 71–84.
https://doi.org/10.1085/jgp.112.1.71
Published: 01 July 1998
View articletitled, Interactions between Multiple Phosphorylation Sites in the Inactivation Particle of a K+ Channel : Insights into the Molecular Mechanism of Protein Kinase C Action
Open the PDF for Interactions between Multiple Phosphorylation Sites in the Inactivation Particle of a K+ Channel : Insights into the Molecular Mechanism of Protein Kinase C Action in another window