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Colleen E. Clancy
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Journal Articles

Mind the midpoints: Rethinking variability in cardiac INa

Colleen E. Clancy
Journal: Journal of General Physiology
Series: Voltage-Gated Na Channels
J Gen Physiol (2025) 157 (5): e202413633.
https://doi.org/10.1085/jgp.202413633
Published: 16 July 2025
View article titled, Mind the midpoints: Rethinking variability in cardiac INa
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Journal Articles

Elucidating molecular mechanisms of protoxin-II state-specific binding to the human NaV1.7 channel

Khoa Ngo, Diego Lopez Mateos, Yanxiao Han, Kyle C. Rouen, Surl-Hee Ahn, Heike Wulff, Colleen E. Clancy, Vladimir Yarov-Yarovoy, Igor Vorobyov
Journal: Journal of General Physiology
J Gen Physiol (2023) 156 (2): e202313368.
https://doi.org/10.1085/jgp.202313368
Published: 21 December 2023
View article titled, Elucidating molecular mechanisms of protoxin-II state-specific binding to the human NaV1.7 channel
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Includes: Supplementary data
Journal Articles

Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling

Laura Guarina, Ariana Neelufar Moghbel, Mohammad S. Pourhosseinzadeh, Robert H. Cudmore, Daisuke Sato, Colleen E. Clancy, Luis Fernando Santana
Journal: Journal of General Physiology
Series: Excitation–Contraction Coupling
J Gen Physiol (2022) 154 (9): e202012613.
https://doi.org/10.1085/jgp.202012613
Published: 28 April 2022
View article titled, Biological noise is a key determinant of the reproducibility and adaptability of cardiac pacemaking and EC coupling
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Journal Articles

A stochastic model of ion channel cluster formation in the plasma membrane

Daisuke Sato, Gonzalo Hernández-Hernández, Collin Matsumoto, Sendoa Tajada, Claudia M. Moreno, Rose E. Dixon, Samantha O’Dwyer, Manuel F. Navedo, James S. Trimmer, Colleen E. Clancy, Marc D. Binder, L. Fernando Santana
Journal: Journal of General Physiology
J Gen Physiol (2019) 151 (9): 1116–1134.
https://doi.org/10.1085/jgp.201912327
Published: 01 August 2019
View article titled, A stochastic model of ion channel cluster formation in the plasma membrane
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Includes: Supplementary data
Journal Articles

Channel Openings Are Necessary but not Sufficient for Use-dependent Block of Cardiac Na+ Channels by Flecainide : Evidence from the Analysis of Disease-linked Mutations

Huajun Liu, Michihiro Tateyama, Colleen E. Clancy, Hugues Abriel, Robert S. Kass
Journal: Journal of General Physiology
J Gen Physiol (2002) 120 (1): 39–51.
https://doi.org/10.1085/jgp.20028558
Published: 24 June 2002
View article titled, Channel Openings Are Necessary but not Sufficient for Use-dependent Block of Cardiac Na+ Channels by Flecainide : Evidence from the Analysis of Disease-linked Mutations
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