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Blockade of TRPV channels by intracellular spermine

Grigory Maksaev, Peng Yuan, Colin G. Nichols

J Gen Physiol (2023) 155 (5): e202213273.

DOI: https://doi.org/10.1085/jgp.202213273

Published: 13 March 2023

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Journal Articles

Seeing spermine blocking of K⁺ ion movement through inward rectifier Kir2.2 channels

Sun-Joo Lee, Colin G. Nichols

J Gen Physiol (2022) 155 (2): e202213144.

DOI: https://doi.org/10.1085/jgp.202213144

Published: 16 December 2022

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Journal Articles

Pore-forming transmembrane domains control ion selectivity and selectivity filter conformation in the KirBac1.1 potassium channel

Marcos Matamoros, Colin G. Nichols

J Gen Physiol (2021) 153 (5): e202012683.

DOI: https://doi.org/10.1085/jgp.202012683

Published: 29 March 2021

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Includes: Supplementary data

Journal Articles

Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

Eva-Maria Zangerl-Plessl, Sun-Joo Lee, Grigory Maksaev, Harald Bernsteiner, Feifei Ren, Peng Yuan, Anna Stary-Weinzinger, Colin G. Nichols

J Gen Physiol (2019) 152 (1): e201912422.

DOI: https://doi.org/10.1085/jgp.201912422

Published: 19 November 2019

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Includes: Supplementary data

Journal Articles

Control of Kir channel gating by cytoplasmic domain interface interactions

William F. Borschel, Shizhen Wang, Sunjoo Lee, Colin G. Nichols

J Gen Physiol (2017) 149 (5): 561–576.

DOI: https://doi.org/10.1085/jgp.201611719

Published: 07 April 2017

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Journal Articles

Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the K_ATP channel

Maria S. Remedi, Jonathan B. Friedman, Colin G. Nichols

J Gen Physiol (2016) 149 (1): 75–84.

DOI: https://doi.org/10.1085/jgp.201611653

Published: 12 December 2016

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Journal Articles

Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids

Sun-Joo Lee, Feifei Ren, Eva-Maria Zangerl-Plessl, Sarah Heyman, Anna Stary-Weinzinger, Peng Yuan, Colin G. Nichols

J Gen Physiol (2016) 148 (3): 227–237.

DOI: https://doi.org/10.1085/jgp.201611616

Published: 15 August 2016

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Includes: Supplementary data

Journal Articles

Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the K_ATP channel

Paige E. Cooper, Monica Sala-Rabanal, Sun Joo Lee, Colin G. Nichols

J Gen Physiol (2015) 146 (6): 527–540.

DOI: https://doi.org/10.1085/jgp.201511495

Published: 30 November 2015

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Journal Articles

Locale and chemistry of spermine binding in the archetypal inward rectifier Kir2.1

Harley T. Kurata, Emily A. Zhu, Colin G. Nichols

J Gen Physiol (2010) 135 (5): 495–508.

DOI: https://doi.org/10.1085/jgp.200910253

Published: 26 April 2010

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Includes: Supplementary data

Journal Articles

KirBac1.1: It's an Inward Rectifying Potassium Channel

Wayland W.L. Cheng, Decha Enkvetchakul, Colin G. Nichols

J Gen Physiol (2009) 133 (3): 295–305.

DOI: https://doi.org/10.1085/jgp.200810125

Published: 09 February 2009

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Journal Articles

Control of Inward Rectifier K Channel Activity by Lipid Tethering of Cytoplasmic Domains

Decha Enkvetchakul, Iana Jeliazkova, Jaya Bhattacharyya, Colin G. Nichols

J Gen Physiol (2007) 130 (3): 329–334.

DOI: https://doi.org/10.1085/jgp.200709764

Published: 13 August 2007

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Journal Articles

The Role of the Cytoplasmic Pore in Inward Rectification of Kir2.1 Channels

Harley T. Kurata, Wayland W. Cheng, Christine Arrabit, Paul A. Slesinger, Colin G. Nichols

J Gen Physiol (2007) 130 (2): 145–155.

DOI: https://doi.org/10.1085/jgp.200709742

Published: 16 July 2007

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Journal Articles

The Polyamine Binding Site in Inward Rectifier K⁺ Channels

Harley T. Kurata, Laurence J. Marton, Colin G. Nichols

J Gen Physiol (2006) 127 (5): 467–480.

DOI: https://doi.org/10.1085/jgp.200509467

Published: 10 April 2006

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Journal Articles

Correction

Harley T. Kurata, L. Revell Phillips, Thierry Rose, Gildas Loussouarn, Stefan Herlitze, Hariolf Fritzenschaft, Decha Enkvetchakul, Colin G. Nichols, Thomas Baukrowitz

J Gen Physiol (2004) 124 (6): 773.

DOI: https://doi.org/10.1085/jgp.200409159111904c

Published: 29 November 2004

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Journal Articles

Molecular Basis of Inward Rectification : Polyamine Interaction Sites Located by Combined Channel and Ligand Mutagenesis

Harley T. Kurata, L. Revell Phillips, Thierry Rose, Gildas Loussouarn, Stefan Herlitze, Hariolf Fritzenschaft, Decha Enkvetchakul, Colin G. Nichols, Thomas Baukrowitz

J Gen Physiol (2004) 124 (5): 541–554.

DOI: https://doi.org/10.1085/jgp.200409159

Published: 11 October 2004

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Journal Articles

Ligand-induced Closure of Inward Rectifier Kir6.2 Channels Traps Spermine in the Pore

L. Revell Phillips, Colin G. Nichols

J Gen Physiol (2003) 122 (6): 795–805.

DOI: https://doi.org/10.1085/jgp.200308953

Published: 24 November 2003

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Journal Articles

Structural and Functional Determinants of Conserved Lipid Interaction Domains of Inward Rectifying Kir6.2 Channels

Catherine A. Cukras, Iana Jeliazkova, Colin G. Nichols

J Gen Physiol (2002) 119 (6): 581–591.

DOI: https://doi.org/10.1085/jgp.20028562

Published: 28 May 2002

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Journal Articles

Structural Determinants of Pip₂ Regulation of Inward Rectifier K_ATP Channels

Show-Ling Shyng, Catherine A. Cukras, Jane Harwood, Colin G. Nichols

J Gen Physiol (2000) 116 (5): 599–608.

DOI: https://doi.org/10.1085/jgp.116.5.599

Published: 16 October 2000

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NARROW

Blockade of TRPV channels by intracellular spermine

Seeing spermine blocking of K⁺ ion movement through inward rectifier Kir2.2 channels

Pore-forming transmembrane domains control ion selectivity and selectivity filter conformation in the KirBac1.1 potassium channel

Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

Control of Kir channel gating by cytoplasmic domain interface interactions

Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the K_ATP channel

Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids

Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the K_ATP channel

Locale and chemistry of spermine binding in the archetypal inward rectifier Kir2.1

KirBac1.1: It's an Inward Rectifying Potassium Channel

Control of Inward Rectifier K Channel Activity by Lipid Tethering of Cytoplasmic Domains

The Role of the Cytoplasmic Pore in Inward Rectification of Kir2.1 Channels

The Polyamine Binding Site in Inward Rectifier K⁺ Channels

Correction

Molecular Basis of Inward Rectification : Polyamine Interaction Sites Located by Combined Channel and Ligand Mutagenesis

Ligand-induced Closure of Inward Rectifier Kir6.2 Channels Traps Spermine in the Pore

Structural and Functional Determinants of Conserved Lipid Interaction Domains of Inward Rectifying Kir6.2 Channels

Structural Determinants of Pip₂ Regulation of Inward Rectifier K_ATP Channels

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