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Colin G. Nichols
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Journal Articles

Blockade of TRPV channels by intracellular spermine

In Special Collection:
Physiology of Pain Detection and Processing Collection 2023
Grigory Maksaev, Peng Yuan, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2023) 155 (5): e202213273.
https://doi.org/10.1085/jgp.202213273
Published: 13 March 2023
View articletitled, Blockade of TRPV channels by intracellular spermine
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Journal Articles

Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels

Sun-Joo Lee, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2022) 155 (2): e202213144.
https://doi.org/10.1085/jgp.202213144
Published: 16 December 2022
View articletitled, Seeing spermine blocking of K+ ion movement through inward rectifier Kir2.2 channels
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Journal Articles

Pore-forming transmembrane domains control ion selectivity and selectivity filter conformation in the KirBac1.1 potassium channel

Marcos Matamoros, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2021) 153 (5): e202012683.
https://doi.org/10.1085/jgp.202012683
Published: 29 March 2021
View articletitled, Pore-forming transmembrane domains control ion selectivity and selectivity filter conformation in the KirBac1.1 potassium channel
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Includes: Supplementary data
Journal Articles

Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels

Eva-Maria Zangerl-Plessl, Sun-Joo Lee, Grigory Maksaev, Harald Bernsteiner, Feifei Ren, Peng Yuan, Anna Stary-Weinzinger, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2019) 152 (1): e201912422.
https://doi.org/10.1085/jgp.201912422
Published: 19 November 2019
View articletitled, Atomistic basis of opening and conduction in mammalian inward rectifier potassium (Kir2.2) channels
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Includes: Supplementary data
Journal Articles

Control of Kir channel gating by cytoplasmic domain interface interactions

William F. Borschel, Shizhen Wang, Sunjoo Lee, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2017) 149 (5): 561–576.
https://doi.org/10.1085/jgp.201611719
Published: 07 April 2017
View articletitled, Control of Kir channel gating by cytoplasmic domain interface interactions
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Journal Articles

Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the KATP channel

Maria S. Remedi, Jonathan B. Friedman, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2016) 149 (1): 75–84.
https://doi.org/10.1085/jgp.201611653
Published: 12 December 2016
View articletitled, Diabetes induced by gain-of-function mutations in the Kir6.1 subunit of the KATP channel
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Journal Articles

Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids

Sun-Joo Lee, Feifei Ren, Eva-Maria Zangerl-Plessl, Sarah Heyman, Anna Stary-Weinzinger, Peng Yuan, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2016) 148 (3): 227–237.
https://doi.org/10.1085/jgp.201611616
Published: 15 August 2016
View articletitled, Structural basis of control of inward rectifier Kir2 channel gating by bulk anionic phospholipids
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Includes: Supplementary data
Journal Articles

Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel

Paige E. Cooper, Monica Sala-Rabanal, Sun Joo Lee, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2015) 146 (6): 527–540.
https://doi.org/10.1085/jgp.201511495
Published: 30 November 2015
View articletitled, Differential mechanisms of Cantú syndrome–associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel
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Journal Articles

Locale and chemistry of spermine binding in the archetypal inward rectifier Kir2.1

Harley T. Kurata, Emily A. Zhu, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2010) 135 (5): 495–508.
https://doi.org/10.1085/jgp.200910253
Published: 26 April 2010
View articletitled, Locale and chemistry of spermine binding in the archetypal inward rectifier Kir2.1
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Includes: Supplementary data
Journal Articles

KirBac1.1: It's an Inward Rectifying Potassium Channel

Wayland W.L. Cheng, Decha Enkvetchakul, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2009) 133 (3): 295–305.
https://doi.org/10.1085/jgp.200810125
Published: 09 February 2009
View articletitled, KirBac1.1: It's an Inward Rectifying Potassium Channel
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Journal Articles

Control of Inward Rectifier K Channel Activity by Lipid Tethering of Cytoplasmic Domains

Decha Enkvetchakul, Iana Jeliazkova, Jaya Bhattacharyya, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2007) 130 (3): 329–334.
https://doi.org/10.1085/jgp.200709764
Published: 13 August 2007
View articletitled, Control of Inward Rectifier K Channel Activity by Lipid Tethering of Cytoplasmic Domains
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Journal Articles

The Role of the Cytoplasmic Pore in Inward Rectification of Kir2.1 Channels

Harley T. Kurata, Wayland W. Cheng, Christine Arrabit, Paul A. Slesinger, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2007) 130 (2): 145–155.
https://doi.org/10.1085/jgp.200709742
Published: 16 July 2007
View articletitled, The Role of the Cytoplasmic Pore in Inward Rectification of Kir2.1 Channels
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Journal Articles

The Polyamine Binding Site in Inward Rectifier K+ Channels

Harley T. Kurata, Laurence J. Marton, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2006) 127 (5): 467–480.
https://doi.org/10.1085/jgp.200509467
Published: 10 April 2006
View articletitled, The Polyamine Binding Site in Inward Rectifier K+ Channels
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Journal Articles

Correction

Harley T. Kurata, L. Revell Phillips, Thierry Rose, Gildas Loussouarn, Stefan Herlitze, Hariolf Fritzenschaft, Decha Enkvetchakul, Colin G. Nichols, Thomas Baukrowitz
Journal: Journal of General Physiology
J Gen Physiol (2004) 124 (6): 773.
https://doi.org/10.1085/jgp.200409159111904c
Published: 29 November 2004
View articletitled, Correction
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Journal Articles

Molecular Basis of Inward Rectification : Polyamine Interaction Sites Located by Combined Channel and Ligand Mutagenesis

Harley T. Kurata, L. Revell Phillips, Thierry Rose, Gildas Loussouarn, Stefan Herlitze, Hariolf Fritzenschaft, Decha Enkvetchakul, Colin G. Nichols, Thomas Baukrowitz
Journal: Journal of General Physiology
J Gen Physiol (2004) 124 (5): 541–554.
https://doi.org/10.1085/jgp.200409159
Published: 11 October 2004
View articletitled, Molecular Basis of Inward Rectification : Polyamine Interaction Sites Located by Combined Channel and Ligand Mutagenesis
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Journal Articles

Ligand-induced Closure of Inward Rectifier Kir6.2 Channels Traps Spermine in the Pore

L. Revell Phillips, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2003) 122 (6): 795–805.
https://doi.org/10.1085/jgp.200308953
Published: 24 November 2003
View articletitled, Ligand-induced Closure of Inward Rectifier Kir6.2 Channels Traps Spermine in the Pore
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Journal Articles

Structural and Functional Determinants of Conserved Lipid Interaction Domains of Inward Rectifying Kir6.2 Channels

Catherine A. Cukras, Iana Jeliazkova, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2002) 119 (6): 581–591.
https://doi.org/10.1085/jgp.20028562
Published: 28 May 2002
View articletitled, Structural and Functional Determinants of Conserved Lipid Interaction Domains of Inward Rectifying Kir6.2 Channels
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Journal Articles

Structural Determinants of Pip2 Regulation of Inward Rectifier KATP Channels

Show-Ling Shyng, Catherine A. Cukras, Jane Harwood, Colin G. Nichols
Journal: Journal of General Physiology
J Gen Physiol (2000) 116 (5): 599–608.
https://doi.org/10.1085/jgp.116.5.599
Published: 16 October 2000
View articletitled, Structural Determinants of Pip2 Regulation of Inward Rectifier KATP Channels
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