Regulation of Tension in the Skinned Crayfish Muscle Fiber II. Role of Calcium

Brandt , P. W.; Reuben , J. P.; Grundfest , H.

doi:10.1085/jgp.59.3.305

Article navigation

Article| March 01 1972

Regulation of Tension in the Skinned Crayfish Muscle Fiber : II. Role of Calcium

P. W. Brandt,

P. W. Brandt

From the Department of Anatomy and the Laboratory of Neurophysiology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York 10032, and the Marine Biological Laboratory, Woods Hole, Massachusetts 02543

Search for other works by this author on:

This Site

PubMed

Google Scholar

J. P. Reuben,

J. P. Reuben

From the Department of Anatomy and the Laboratory of Neurophysiology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York 10032, and the Marine Biological Laboratory, Woods Hole, Massachusetts 02543

Search for other works by this author on:

This Site

PubMed

Google Scholar

H. Grundfest

From the Department of Anatomy and the Laboratory of Neurophysiology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York 10032, and the Marine Biological Laboratory, Woods Hole, Massachusetts 02543

Search for other works by this author on:

This Site

PubMed

Google Scholar

Author and Article Information

P. W. Brandt

From the Department of Anatomy and the Laboratory of Neurophysiology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York 10032, and the Marine Biological Laboratory, Woods Hole, Massachusetts 02543

J. P. Reuben

From the Department of Anatomy and the Laboratory of Neurophysiology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York 10032, and the Marine Biological Laboratory, Woods Hole, Massachusetts 02543

H. Grundfest

From the Department of Anatomy and the Laboratory of Neurophysiology, Department of Neurology, College of Physicians and Surgeons, Columbia University, New York 10032, and the Marine Biological Laboratory, Woods Hole, Massachusetts 02543

Received: July 14 1971

Online ISSN: 1540-7748

Print ISSN: 0022-1295

1972

J Gen Physiol (1972) 59 (3): 305–317.

https://doi.org/10.1085/jgp.59.3.305

Tension outputs were measured in skinned crayfish muscle fibers exposed to solutions variously buffered for both Mg-adenosine triphosphate (ATP) and Ca. Two types of data are shown, relating tension and substrate concentration with different levels of Ca present, or tension and calcium concentration at different levels of substrate. The data are fitted by curves calculated from a general equation for substrate inhibition. The equation is based on the schema that both tension and relaxation are induced by the substrate and that the relaxing effect of excess substrate is repressed by calcium. The physiological findings of the present work are similar to data obtained by others on biochemical model systems of the contractile proteins.

This content is only available as a PDF.

1972

You do not currently have access to this content.

Don't already have an account? Register

You could not be signed in. Please check your email address / username and password and try again.

Regulation of Tension in the Skinned Crayfish Muscle Fiber : II. Role of Calcium

Sign in

Client Account

Sign in via your Institution

Suggested Content

Email alerts