1. Sections of Avena coleoptiles are found to show a considerable elongation when suspended in solutions of growth substance.
2. This elongation does not take place in the absence of O2 and is inhibited by KCN and phenylurethane.
3. The rate of respiration of sections of coleoptiles is increased by the addition of growth substance in concentrations which cause growth. High concentrations of growth substance inhibit growth and also respiration.
4. The increase in respiration is inhibited by KCN and phenylurethane in the concentrations which inhibit normal respiration. These concentrations are the same as those which inhibit growth.
5. From 2, 3, and 4, it seems possible that the increase in respiration caused by growth substance may be an essential part of its action in growth.