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Journal Articles

RNA recognition by human TLR8 can lead to autoimmune inflammation

Cristiana Guiducci, Mei Gong, Alma-Martina Cepika, Zhaohui Xu, Claudio Tripodo, Lynda Bennett, Chad Crain, Pierre Quartier, John J. Cush, Virginia Pascual, Robert L. Coffman, Franck J. Barrat

J Exp Med (2013) 210 (13): 2903–2919.

https://doi.org/10.1084/jem.20131044

Published: 25 November 2013

View article titled, RNA recognition by human TLR8 can lead to autoimmune inflammation

Includes: Supplementary data

Journal Articles

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

Cristiana Guiducci, Claudio Tripodo, Mei Gong, Sabina Sangaletti, Mario P. Colombo, Robert L. Coffman, Franck J. Barrat

J Exp Med (2010) 207 (13): 2931–2942.

https://doi.org/10.1084/jem.20101048

Published: 29 November 2010

View article titled, Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

Includes: Supplementary data

Journal Articles

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

Cristiana Guiducci, Cristina Ghirelli, Marie-Annick Marloie-Provost, Tracy Matray, Robert L. Coffman, Yong-Jun Liu, Franck J. Barrat, Vassili Soumelis

J Exp Med (2008) 205 (2): 315–322.

https://doi.org/10.1084/jem.20070763

Published: 28 January 2008

View article titled, PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

Includes: Supplementary data

Journal Articles

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation

Cristiana Guiducci, Gary Ott, Jean H. Chan, Emily Damon, Carlo Calacsan, Tracy Matray, Kyung-Dall Lee, Robert L. Coffman, Franck J. Barrat

J Exp Med (2006) 203 (8): 1999–2008.

https://doi.org/10.1084/jem.20060401

Published: 24 July 2006

View article titled, Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation

Includes: Supplementary data

Journal Articles

Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction

Edith M. Hessel, Mabel Chu, Jennifer O. Lizcano, Bonnie Chang, Nancy Herman, Sariah A. Kell, Marsha Wills-Karp, Robert L. Coffman

J Exp Med (2005) 202 (11): 1563–1573.

https://doi.org/10.1084/jem.20050631

Published: 28 November 2005

View article titled, Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction

Includes: Supplementary data

Journal Articles

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

Franck J. Barrat, Thea Meeker, Josh Gregorio, Jean H. Chan, Satoshi Uematsu, Shizuo Akira, Bonnie Chang, Omar Duramad, Robert L. Coffman

J Exp Med (2005) 202 (8): 1131–1139.

https://doi.org/10.1084/jem.20050914

Published: 17 October 2005

View article titled, Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

Includes: Supplementary data

Journal Articles

Nonhuman primate models of asthma

Robert L. Coffman, Edith M. Hessel

J Exp Med (2005) 201 (12): 1875–1879.

https://doi.org/10.1084/jem.20050901

Published: 20 June 2005

View article titled, Nonhuman primate models of asthma

Journal Articles

T cells that cannot respond to TGF-β escape control by CD4⁺CD25⁺ regulatory T cells

Linda Fahlén, Simon Read, Leonid Gorelik, Stephen D. Hurst, Robert L. Coffman, Richard A. Flavell, Fiona Powrie

J Exp Med (2005) 201 (5): 737–746.

https://doi.org/10.1084/jem.20040685

Published: 07 March 2005

View article titled, T cells that cannot respond to TGF-β escape control by CD4+CD25+ regulatory T cells

Includes: Supplementary data

Journal Articles

In Vitro Generation of Interleukin 10–producing Regulatory CD4⁺ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines

Franck J. Barrat, Daniel J. Cua, André Boonstra, David F. Richards, Chad Crain, Huub F. Savelkoul, René de Waal-Malefyt, Robert L. Coffman, Catherine M. Hawrylowicz, Anne O'Garra

J Exp Med (2002) 195 (5): 603–616.

https://doi.org/10.1084/jem.20011629

Published: 04 March 2002

View article titled, In Vitro Generation of Interleukin 10–producing Regulatory CD4+ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines

Journal Articles

Interferon γ Signaling Alters the Function of T Helper Type 1 Cells

Gregory Z. Tau, Thierry von der Weid, Binfeng Lu, Simone Cowan, Marina Kvatyuk, Alessandra Pernis, Giorgio Cattoretti, Ned S. Braunstein, Robert L. Coffman, Paul B. Rothman

J Exp Med (2000) 192 (7): 977–986.

https://doi.org/10.1084/jem.192.7.977

Published: 02 October 2000

View article titled, Interferon γ Signaling Alters the Function of T Helper Type 1 Cells

Journal Articles

An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

Chrystelle Asseman, Smita Mauze, Michael W. Leach, Robert L. Coffman, Fiona Powrie

J Exp Med (1999) 190 (7): 995–1004.

https://doi.org/10.1084/jem.190.7.995

Published: 04 October 1999

View article titled, An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

Journal Articles

Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis

Daniel J. Cua, Herve Groux, David R. Hinton, Stephen A. Stohlman, Robert L. Coffman

J Exp Med (1999) 189 (6): 1005–1010.

https://doi.org/10.1084/jem.189.6.1005

Published: 15 March 1999

View article titled, Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis

Journal Articles

Aerosol-induced Immunoglobulin (Ig)-E Unresponsiveness to Ovalbumin Does Not Require CD8⁺ or T Cell Receptor (TCR)-γ/δ⁺ T Cells or Interferon (IFN)-γ in a Murine Model of Allergen Sensitization

Brian W.P. Seymour, Laurel J. Gershwin, Robert L. Coffman

J Exp Med (1998) 187 (5): 721–731.

https://doi.org/10.1084/jem.187.5.721

Published: 02 March 1998

View article titled, Aerosol-induced Immunoglobulin (Ig)-E Unresponsiveness to Ovalbumin Does Not Require CD8+ or T Cell Receptor (TCR)-γ/δ+ T Cells or Interferon (IFN)-γ in a Murine Model of Allergen Sensitization

Journal Articles

Behavior of Visceral Leishmania donovani in an Experimentally Induced T Helper Cell 2 (Th2)-Associated Response Model

Henry W. Murray, June Hariprashad, Robert L. Coffman

J Exp Med (1997) 185 (5): 867–874.

https://doi.org/10.1084/jem.185.5.867

Published: 03 March 1997

View article titled, Behavior of Visceral Leishmania donovani in an Experimentally Induced T Helper Cell 2 (Th2)-Associated Response Model

Journal Articles

Multiple Pathways for the Initiation of T Helper 2 (Th2) Responses

Robert L. Coffman, Thierry Weid

J Exp Med (1997) 185 (3): 373–376.

https://doi.org/10.1084/jem.185.3.373

Published: 03 February 1997

View article titled, Multiple Pathways for the Initiation of T Helper 2 (Th2) Responses

NARROW

RNA recognition by human TLR8 can lead to autoimmune inflammation

Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9

PI3K is critical for the nuclear translocation of IRF-7 and type I IFN production by human plasmacytoid predendritic cells in response to TLR activation

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation

Immunostimulatory oligonucleotides block allergic airway inflammation by inhibiting Th2 cell activation and IgE-mediated cytokine induction

Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus

Nonhuman primate models of asthma

T cells that cannot respond to TGF-β escape control by CD4⁺CD25⁺ regulatory T cells

In Vitro Generation of Interleukin 10–producing Regulatory CD4⁺ T Cells Is Induced by Immunosuppressive Drugs and Inhibited by T Helper Type 1 (Th1)– and Th2-inducing Cytokines

Interferon γ Signaling Alters the Function of T Helper Type 1 Cells

An Essential Role for Interleukin 10 in the Function of Regulatory T Cells That Inhibit Intestinal Inflammation

Transgenic Interleukin 10 Prevents Induction of Experimental Autoimmune Encephalomyelitis

Aerosol-induced Immunoglobulin (Ig)-E Unresponsiveness to Ovalbumin Does Not Require CD8⁺ or T Cell Receptor (TCR)-γ/δ⁺ T Cells or Interferon (IFN)-γ in a Murine Model of Allergen Sensitization

Behavior of Visceral Leishmania donovani in an Experimentally Induced T Helper Cell 2 (Th2)-Associated Response Model

Multiple Pathways for the Initiation of T Helper 2 (Th2) Responses

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