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Léna Gélard
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Journal Articles

A CARMIL2 gain-of-function mutation suffices to trigger most CD28 costimulatory functions in vivo

Fanghui Zhang, Javier Celis-Gutierrez, Lichen Zhang, Valentin Mellado, Léna Gelard, Sophie Panigot, Daiki Mori, Liaoxun Lu, Guillaume Voisinne, Carine Vilarnau Wolek, Marielle Mello, Odile Burlet-Schiltz, Anne Gonzalez de Peredo, Frédéric Fiore, Romain Roncagalli, Yinming Liang, Marie Malissen, Bernard Malissen
Journal: Journal of Experimental Medicine
J Exp Med (2025) 222 (8): e20250339.
https://doi.org/10.1084/jem.20250339
Published: 22 May 2025
View articletitled, A CARMIL2 gain-of-function mutation suffices to trigger most CD28 costimulatory functions in vivo
Open the PDF for A CARMIL2 gain-of-function mutation suffices to trigger most CD28 costimulatory functions in vivo in another window
Includes: Supplementary data
Journal Articles

Defective LAT signalosome pathology in mice mimics human IgG4-related disease at single-cell level

Anais Joachim, Rudy Aussel, Léna Gélard, Fanghui Zhang, Daiki Mori, Claude Grégoire, Sergio Villazala Merino, Mauro Gaya, Yinming Liang, Marie Malissen, Bernard Malissen
Journal: Journal of Experimental Medicine
J Exp Med (2023) 220 (11): e20231028.
https://doi.org/10.1084/jem.20231028
Published: 25 August 2023
View articletitled, Defective LAT signalosome pathology in mice mimics human IgG4-related disease at single-cell level
Open the PDF for Defective LAT signalosome pathology in mice mimics human IgG4-related disease at single-cell level in another window
Includes: Supplementary data