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Journal Articles

Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis

Merlijn H. Kaaij, Melissa N. van Tok, Iris C. Blijdorp, Carmen A. Ambarus, Michael Stock, Désiree Pots, Véronique L. Knaup, Marietta Armaka, Eleni Christodoulou-Vafeiadou, Tessa K. van Melsen, Huriatul Masdar, Harry J.P.P. Eskes, Nataliya G. Yeremenko, George Kollias, Georg Schett, Sander W. Tas, Leonie M. van Duivenvoorde, Dominique L.P. Baeten

J Exp Med (2020) 217 (10): e20200288.

https://doi.org/10.1084/jem.20200288

Published: 14 July 2020

View article titled, Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis

Journal Articles

Unfolding innate mechanisms in the cancer microenvironment: The emerging role of the mesenchyme

In Special Collection:

JEM 2020 Update on Cancer Immunology and Immunotherapy

Vasiliki Koliaraki, Ana Henriques, Alejandro Prados, George Kollias

J Exp Med (2020) 217 (4): e20190457.

https://doi.org/10.1084/jem.20190457

Published: 11 February 2020

View article titled, Unfolding innate mechanisms in the cancer microenvironment: The emerging role of the mesenchyme

Journal Articles

IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer

Vasiliki Koliaraki, Manolis Pasparakis, George Kollias

J Exp Med (2015) 212 (13): 2235–2251.

https://doi.org/10.1084/jem.20150542

Published: 30 November 2015

View article titled, IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer

Journal Articles

Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis

Ioanna Nikitopoulou, Nikos Oikonomou, Emmanuel Karouzakis, Ioanna Sevastou, Nefeli Nikolaidou-Katsaridou, Zhenwen Zhao, Vassilis Mersinias, Maria Armaka, Yan Xu, Masayuki Masu, Gordon B. Mills, Steffen Gay, George Kollias, Vassilis Aidinis

J Exp Med (2012) 209 (5): 925–933.

https://doi.org/10.1084/jem.20112012

Published: 09 April 2012

View article titled, Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis

Includes: Supplementary data

Journal Articles

Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production

Sotiria Tzima, Panayiotis Victoratos, Ksanthi Kranidioti, Maria Alexiou, George Kollias

J Exp Med (2009) 206 (5): 1167–1179.

https://doi.org/10.1084/jem.20081582

Published: 27 April 2009

View article titled, Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production

Includes: Supplementary data

Journal Articles

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

Maria Armaka, Maria Apostolaki, Peggy Jacques, Dimitris L. Kontoyiannis, Dirk Elewaut, George Kollias

J Exp Med (2008) 205 (2): 331–337.

https://doi.org/10.1084/jem.20070906

Published: 04 February 2008

View article titled, Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

Includes: Supplementary data

Journal Articles

Tumor Necrosis Factor (TNF) Receptor Shedding Controls Thresholds of Innate Immune Activation That Balance Opposing TNF Functions in Infectious and Inflammatory Diseases

Sofia Xanthoulea, Manolis Pasparakis, Stavroula Kousteni, Cord Brakebusch, David Wallach, Jan Bauer, Hans Lassmann, George Kollias

J Exp Med (2004) 200 (3): 367–376.

https://doi.org/10.1084/jem.20040435

Published: 02 August 2004

View article titled, Tumor Necrosis Factor (TNF) Receptor Shedding Controls Thresholds of Innate Immune Activation That Balance Opposing TNF Functions in Infectious and Inflammatory Diseases

Journal Articles

Genetic Dissection of the Cellular Pathways and Signaling Mechanisms in Modeled Tumor Necrosis Factor–induced Crohn's-like Inflammatory Bowel Disease

Dimitris Kontoyiannis, George Boulougouris, Menelaos Manoloukos, Maria Armaka, Maria Apostolaki, Theresa Pizarro, Alexey Kotlyarov, Irmgard Forster, Richard Flavell, Matthias Gaestel, Philip Tsichlis, Fabio Cominelli, George Kollias

J Exp Med (2002) 196 (12): 1563–1574.

https://doi.org/10.1084/jem.20020281

Published: 09 December 2002

View article titled, Genetic Dissection of the Cellular Pathways and Signaling Mechanisms in Modeled Tumor Necrosis Factor–induced Crohn's-like Inflammatory Bowel Disease

Journal Articles

Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level: Implications for Pathogenesis and Therapy of Autoimmune Demyelination

George Kassiotis, George Kollias

J Exp Med (2001) 193 (4): 427–434.

https://doi.org/10.1084/jem.193.4.427

Published: 12 February 2001

View article titled, Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level: <subtitle>Implications for Pathogenesis and Therapy of Autoimmune Demyelination</subtitle>

Journal Articles

Mast Cells Control Neutrophil Recruitment during T Cell–Mediated Delayed-Type Hypersensitivity Reactions through Tumor Necrosis Factor and Macrophage Inflammatory Protein 2

Tilo Biedermann, Manfred Kneilling, Reinhard Mailhammer, Konrad Maier, Christian A. Sander, George Kollias, Steven L. Kunkel, Lothar Hültner, Martin Röcken

J Exp Med (2000) 192 (10): 1441–1452.

https://doi.org/10.1084/jem.192.10.1441

Published: 13 November 2000

View article titled, Mast Cells Control Neutrophil Recruitment during T Cell–Mediated Delayed-Type Hypersensitivity Reactions through Tumor Necrosis Factor and Macrophage Inflammatory Protein 2

Journal Articles

The c-kit Ligand, Stem Cell Factor, Can Enhance Innate Immunity Through Effects on Mast Cells

Marcus Maurer, Bernd Echtenacher, Lothar Hültner, George Kollias, Daniela N. Männel, Keith E. Langley, Stephen J. Galli

J Exp Med (1998) 188 (12): 2343–2348.

https://doi.org/10.1084/jem.188.12.2343

Published: 21 December 1998

View article titled, The c-kit Ligand, Stem Cell Factor, Can Enhance Innate Immunity Through Effects on Mast Cells

Journal Articles

A Critical Role of the p75 Tumor Necrosis Factor Receptor (p75TNF-R) in Organ Inflammation Independent of TNF, Lymphotoxin α, or the p55TNF-R

Eleni Douni, George Kollias

J Exp Med (1998) 188 (7): 1343–1352.

https://doi.org/10.1084/jem.188.7.1343

Published: 05 October 1998

View article titled, A Critical Role of the p75 Tumor Necrosis Factor Receptor (p75TNF-R) in Organ Inflammation Independent of TNF, Lymphotoxin α, or the p55TNF-R

Journal Articles

Complementation of Lymphotoxin α Knockout Mice with Tumor Necrosis Factor–expressing Transgenes Rectifies Defective Splenic Structure and Function

Lena Alexopoulou, Manolis Pasparakis, George Kollias

J Exp Med (1998) 188 (4): 745–754.

https://doi.org/10.1084/jem.188.4.745

Published: 17 August 1998

View article titled, Complementation of Lymphotoxin α Knockout Mice with Tumor Necrosis Factor–expressing Transgenes Rectifies Defective Splenic Structure and Function

Journal Articles

Interleukin 6 Is Required for the Development of Collagen-induced Arthritis

Tonino Alonzi, Elena Fattori, Domenico Lazzaro, Patrizia Costa, Lesley Probert, George Kollias, Fabrizio De Benedetti, Valeria Poli, Gennaro Ciliberto

J Exp Med (1998) 187 (4): 461–468.

https://doi.org/10.1084/jem.187.4.461

Published: 16 February 1998

View article titled, Interleukin 6 Is Required for the Development of Collagen-induced Arthritis

Journal Articles

Chronic Tumor Necrosis Factor Alters T Cell Responses by Attenuating T Cell Receptor Signaling

Andrew P. Cope, Roland S. Liblau, Xiao-Dong Yang, Mauro Congia, Carlo Laudanna, Robert D. Schreiber, Lesley Probert, George Kollias, Hugh O. McDevitt

J Exp Med (1997) 185 (9): 1573–1584.

https://doi.org/10.1084/jem.185.9.1573

Published: 05 May 1997

View article titled, Chronic Tumor Necrosis Factor Alters T Cell Responses by Attenuating T Cell Receptor Signaling

NARROW

Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis

Unfolding innate mechanisms in the cancer microenvironment: The emerging role of the mesenchyme

IKKβ in intestinal mesenchymal cells promotes initiation of colitis-associated cancer

Autotaxin expression from synovial fibroblasts is essential for the pathogenesis of modeled arthritis

Myeloid heme oxygenase–1 regulates innate immunity and autoimmunity by modulating IFN-β production

Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases

Tumor Necrosis Factor (TNF) Receptor Shedding Controls Thresholds of Innate Immune Activation That Balance Opposing TNF Functions in Infectious and Inflammatory Diseases

Genetic Dissection of the Cellular Pathways and Signaling Mechanisms in Modeled Tumor Necrosis Factor–induced Crohn's-like Inflammatory Bowel Disease

Uncoupling the Proinflammatory from the Immunosuppressive Properties of Tumor Necrosis Factor (Tnf) at the P55 TNF Receptor Level: Implications for Pathogenesis and Therapy of Autoimmune Demyelination

Mast Cells Control Neutrophil Recruitment during T Cell–Mediated Delayed-Type Hypersensitivity Reactions through Tumor Necrosis Factor and Macrophage Inflammatory Protein 2

The c-kit Ligand, Stem Cell Factor, Can Enhance Innate Immunity Through Effects on Mast Cells

A Critical Role of the p75 Tumor Necrosis Factor Receptor (p75TNF-R) in Organ Inflammation Independent of TNF, Lymphotoxin α, or the p55TNF-R

Complementation of Lymphotoxin α Knockout Mice with Tumor Necrosis Factor–expressing Transgenes Rectifies Defective Splenic Structure and Function

Interleukin 6 Is Required for the Development of Collagen-induced Arthritis

Chronic Tumor Necrosis Factor Alters T Cell Responses by Attenuating T Cell Receptor Signaling

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