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LIME : A New Membrane Raft-associated Adaptor Protein Involved in CD4 and CD8 Coreceptor Signaling Preliminary reports (abstracts, poster, and oral communications) on some aspects of this work were presented at the ELSO2002 Meeting, Nice, June 29–July 3, 2002, 5th EFIS Tatra Immunology Conference, Tatranske Zruby, September 7–11, 2002, and 15th EFIS Meeting, Rhodes, June 2003. Abbreviations used in this paper: Cbp, Csk-binding protein; LAT, linker for activation of T cells; LAB, linker for activation of B cells; LIME, Lck-interacting molecule; NTAL, non–T cell activation linker; PAG, phosphoprotein associated with glycosphingolipid-enriched microdomains; PBL, peripheral blood leukocytes; PHA, phytohemagglutinin; PLCγ, phospholipase Cγ; PTK, protein tyrosine kinase; P-Tyr, phosphotyrosine; SH Src homology; TRAP, transmembrane adaptor protein; TRIM, TCR-interacting molecule.

Naděžda Brdičková, Tomáš Brdička, Pavla Angelisová, Ondrej Horváth, Jiří Špička, Ivan Hilgert, Jan Pačes, Luca Simeoni, Stefanie Kliche, Camilla Merten, Burkhart Schraven, Václav Hořejší

J Exp Med (2003) 198 (10): 1453–1462.

https://doi.org/10.1084/jem.20031484

Published: 10 November 2003

View article titled, LIME : <subtitle>A New Membrane Raft-associated Adaptor Protein Involved in CD4 and CD8 Coreceptor Signaling Preliminary reports (abstracts, poster, and oral communications) on some aspects of this work were presented at the ELSO2002 Meeting, Nice, June 29–July 3, 2002, 5th EFIS Tatra Immunology Conference, Tatranske Zruby, September 7–11, 2002, and 15th EFIS Meeting, Rhodes, June 2003. <em>Abbreviations used in this paper:</em> Cbp, Csk-binding protein; LAT, linker for activation of T cells; LAB, linker for activation of B cells; LIME, Lck-interacting molecule; NTAL, non–T cell activation linker; PAG, phosphoprotein associated with glycosphingolipid-enriched microdomains; PBL, peripheral blood leukocytes; PHA, phytohemagglutinin; PLCγ, phospholipase Cγ; PTK, protein tyrosine kinase; P-Tyr, phosphotyrosine; SH Src homology; TRAP, transmembrane adaptor protein; TRIM, TCR-interacting molecule. </subtitle>

Journal Articles

Non–T Cell Activation Linker (NTAL) : A Transmembrane Adaptor Protein Involved in Immunoreceptor Signaling

Tomáš Brdička, Martin Imrich, Pavla Angelisová, Naděžda Brdičková, Ondrej Horváth, Jiří Špička, Ivan Hilgert, Petra Lusková, Petr Dráber, Petr Novák, Niklas Engels, Jürgen Wienands, Luca Simeoni, Jan Österreicher, Enrique Aguado, Marie Malissen, Burkhart Schraven, Václav Hořejší

J Exp Med (2002) 196 (12): 1617–1626.

https://doi.org/10.1084/jem.20021405

Published: 16 December 2002

View article titled, Non–T Cell Activation Linker (NTAL) : <subtitle>A Transmembrane Adaptor Protein Involved in Immunoreceptor Signaling </subtitle>

Journal Articles

The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain

Henning Kirchgessner, Jes Dietrich, Jeanette Scherer, Pia Isomäki, Vladimir Korinek, Ivan Hilgert, Eddy Bruyns, Albrecht Leo, Andrew P. Cope, Burkhart Schraven

J Exp Med (2001) 193 (11): 1269–1284.

https://doi.org/10.1084/jem.193.11.1269

Published: 04 June 2001

View article titled, The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain

Journal Articles

Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

Tomás̆ Brdic̆ka, Dagmar Pavlis̆tová, Albrecht Leo, Eddy Bruyns, Vladimír Kor̆ínek, Pavla Angelisová, Jeanette Scherer, Andrej Shevchenko, Anna Shevchenko, Ivan Hilgert, Jan C̆erný, Karel Drbal, Yasuhiro Kuramitsu, Birgit Kornacker, Václav Hor̆ejs̆í, Burkhart Schraven

J Exp Med (2000) 191 (9): 1591–1604.

https://doi.org/10.1084/jem.191.9.1591

Published: 01 May 2000

View article titled, Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

Journal Articles

SHP2-interacting Transmembrane Adaptor Protein (SIT), A Novel Disulfide-linked Dimer Regulating Human T Cell Activation

Anne Marie-Cardine, Henning Kirchgessner, Eddy Bruyns, Andrej Shevchenko, Matthias Mann, Frank Autschbach, Sheldon Ratnofsky, Stefan Meuer, Burkhart Schraven

J Exp Med (1999) 189 (8): 1181–1194.

https://doi.org/10.1084/jem.189.8.1181

Published: 19 April 1999

View article titled, SHP2-interacting Transmembrane Adaptor Protein (SIT), A Novel Disulfide-linked Dimer Regulating Human T Cell Activation

Journal Articles

T Cell Receptor (TCR) Interacting Molecule (TRIM), A Novel Disulfide-linked Dimer Associated with the TCR–CD3–ζ Complex, Recruits Intracellular Signaling Proteins to the Plasma Membrane

Eddy Bruyns, Anne Marie-Cardine, Henning Kirchgessner, Karin Sagolla, Andrej Shevchenko, Matthias Mann, Frank Autschbach, Armand Bensussan, Stefan Meuer, Burkhart Schraven

J Exp Med (1998) 188 (3): 561–575.

https://doi.org/10.1084/jem.188.3.561

Published: 03 August 1998

View article titled, T Cell Receptor (TCR) Interacting Molecule (TRIM), A Novel Disulfide-linked Dimer Associated with the TCR–CD3–ζ Complex, Recruits Intracellular Signaling Proteins to the Plasma Membrane

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Non–T Cell Activation Linker (NTAL) : A Transmembrane Adaptor Protein Involved in Immunoreceptor Signaling

The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain

Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

SHP2-interacting Transmembrane Adaptor Protein (SIT), A Novel Disulfide-linked Dimer Regulating Human T Cell Activation

T Cell Receptor (TCR) Interacting Molecule (TRIM), A Novel Disulfide-linked Dimer Associated with the TCR–CD3–ζ Complex, Recruits Intracellular Signaling Proteins to the Plasma Membrane

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Non–T Cell Activation Linker (NTAL) : A Transmembrane Adaptor Protein Involved in Immunoreceptor Signaling

The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr ζ Chain

Phosphoprotein Associated with Glycosphingolipid-Enriched Microdomains (Pag), a Novel Ubiquitously Expressed Transmembrane Adaptor Protein, Binds the Protein Tyrosine Kinase Csk and Is Involved in Regulation of T Cell Activation

SHP2-interacting Transmembrane Adaptor Protein (SIT), A Novel Disulfide-linked Dimer Regulating Human T Cell Activation

T Cell Receptor (TCR) Interacting Molecule (TRIM), A Novel Disulfide-linked Dimer Associated with the TCR–CD3–ζ Complex, Recruits Intracellular Signaling Proteins to the Plasma Membrane

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