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Metabolism Signaling

JEM has been a pioneer in many fields, including the cross-over between metabolism and immunity. We are pleased to present a special collection featuring original research articles, brief definitive reports, and reviews published at JEM in the last 12 months covering a broad range of topics including oxidative metabolism in tumor-associated macrophages (TAMs), nutrition uptake and communication network changes under different diets, protein synthesis in T cells and amino acid usage in ILCs, as well as repurposing a tricyclic antidepressant as a fatty acid uptake inhibitor for cancer treatment. Original research on transcriptional network changes and lysosomal inhibition signaling are also featured.

We hope you will enjoy reading this collection and encourage your feedback on Twitter (@JExpMed). To learn more about JEM, or if you are interested in submitting work in this field, please visit our Instructions for Authors or reach out to our team of editorsSign up to receive future special collections here.

Image © 2022 González-Loyola et al.

Special Collection Image
Michael A. Gonzalez; Daniel R. Lu; Maryam Yousefi; Ashley Kroll; Chen Hao Lo; Carlos G. Briseño; J. E. Vivienne Watson; Sergey Novitskiy; Vanessa Arias; Hong Zhou; Andres Plata Stapper; Min K. Tsai; Emily L. Ashkin; Christopher W. Murray; Chi-Ming Li; Monte M. Winslow; Kristin V. Tarbell
DOI: 10.1084/jem.20221472
Yu-Chen Wang; Yang Cao; Calvin Pan; Zhiqiang Zhou; Lili Yang; Aldons J. Lusis
DOI: 10.1084/jem.20221437
Giorgia Benegiamo; Giacomo V.G. von Alvensleben; Sandra Rodríguez-López; Ludger J.E. Goeminne; Alexis M. Bachmann; Jean-David Morel; Ellen Broeckx; Jing Ying Ma; Vinicius Carreira; Sameh A. Youssef; Nabil Azhar; Dermot F. Reilly; Katharine D’Aquino; Shannon Mullican; Maroun Bou-Sleiman; Johan Auwerx
DOI: 10.1084/jem.20221738
Mark R. Silvis; Dilru Silva; Riley Rohweder; Sophia Schuman; Swapna Gudipaty; Amanda Truong; Jeffrey Yap; Kajsa Affolter; Martin McMahon; Conan Kinsey
DOI: 10.1084/jem.20221524
Lomon So; Kazushige Obata-Ninomiya; Alex Hu; Virginia S. Muir; Ayako Takamori; Jing Song; Jane H. Buckner; Ram Savan; Steven F. Ziegler
DOI: 10.1084/jem.20221676
Suzanne H. Hodge; Maria Z. Krauss; Irem Kaymak; James I. King; Andrew J.M. Howden; Gordana Panic; Richard K. Grencis; Jonathan R. Swann; Linda V. Sinclair; Matthew R. Hepworth
DOI: 10.1084/jem.20221073
Qiaoyun Chu; Jing An; Ping Liu; Yihan Song; Xuewei Zhai; Ronghui Yang; Jing Niu; Chuanzhen Yang; Binghui Li
DOI: 10.1084/jem.20221316
Huiyang Yu; Nicolas Jacquelot; Gabrielle T. Belz
DOI: 10.1084/jem.20221140
Catalina Cosovanu; Philipp Resch; Stefan Jordan; Andrea Lehmann; Markus Ralser; Vadim Farztdinov; Joachim Spranger; Michael Mülleder; Sebastian Brachs; Christian Neumann
DOI: 10.1084/jem.20220233
Alejandra González-Loyola; Jeremiah Bernier-Latmani; Irena Roci; Tania Wyss; Jakob Langer; Stephan Durot; Olivia Munoz; Borja Prat-Luri; Mauro Delorenzi; Matthias P. Lutolf; Nicola Zamboni; Grégory Verdeil; Tatiana V. Petrova
DOI: 10.1084/jem.20212418
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