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2020 Nobel Prize Collection

2020 Nobel Prize Collection
The Nobel Prize in Physiology or Medicine 2020 was awarded jointly to Charles M. Rice of The Rockefeller University, Michael Houghton of the University of Alberta, and Harvey J. Alter of the NIH for the discovery of Hepatitis C virus. Their contributions made possible blood tests and new medicines against blood-borne hepatitis, which is a major cause of liver cancer and cirrhosis. WHO estimated that in 2016, approximately 399,000 people died from hepatitis C, mostly from cirrhosis and hepatocellular carcinoma (primary liver cancer). While the statistics are sobering, many more lives would have been lost if it were not for seminal work by these scientists. We celebrate their winning the 2020 Nobel Prize in Physiology or Medicine with a collection of Journal of Experimental Medicine (JEM) and Journal of Cell Biology (JCB) studies published by Rice and Houghton on the topics of Hepatitis C virus, yellow fever, and SARS-CoV-2.

Illustration: Niklas Elmehed. © Nobel Media AB 2020

Special Collection Image
Technical Advances and Resources
Fabian Schmidt; Yiska Weisblum; Frauke Muecksch; Hans-Heinrich Hoffmann; Eleftherios Michailidis; Julio C.C. Lorenzi; Pilar Mendoza; Magdalena Rutkowska; Eva Bednarski; Christian Gaebler; Marianna Agudelo; Alice Cho; Zijun Wang; Anna Gazumyan; Melissa Cipolla; Marina Caskey; Davide F. Robbiani; Michel C. Nussenzweig; Charles M. Rice; Theodora Hatziioannou; Paul D. Bieniasz
DOI: 10.1084/jem.20201181
Article
Nicholas Hernandez; Giorgia Bucciol; Leen Moens; Jérémie Le Pen; Mohammad Shahrooei; Ekaterini Goudouris; Afshin Shirkani; Majid Changi-Ashtiani; Hassan Rokni-Zadeh; Esra Hazar Sayar; Ismail Reisli; Alain Lefevre-Utile; Dick Zijlmans; Andrea Jurado; Ruben Pholien; Scott Drutman; Serkan Belkaya; Aurelie Cobat; Robbert Boudewijns; Dirk Jochmans; Johan Neyts; Yoann Seeleuthner; Lazaro Lorenzo-Diaz; Chibuzo Enemchukwu; Ian Tietjen; Hans-Heinrich Hoffmann; Mana Momenilandi; Laura Pöyhönen; Marilda M. Siqueira; Sheila M. Barbosa de Lima; Denise C. de Souza Matos; Akira Homma; Maria de Lourdes S. Maia; Tamiris Azamor da Costa Barros; Patricia Mouta Nunes de Oliveira; Emersom Ciclini Mesquita; Rik Gijsbers; Shen-Ying Zhang; Stephen J. Seligman; Laurent Abel; Paul Hertzog; Nico Marr; Reinaldo de Menezes Martins; Isabelle Meyts; Qian Zhang; Margaret R. MacDonald; Charles M. Rice; Jean-Laurent Casanova; Emmanuelle Jouanguy; Xavier Bossuyt
DOI: 10.1084/jem.20182295
Article
Serkan Belkaya; Eleftherios Michailidis; Cecilia B. Korol; Mohammad Kabbani; Aurélie Cobat; Paul Bastard; Yoon Seung Lee; Nicholas Hernandez; Scott Drutman; Ype P. de Jong; Eric Vivier; Julie Bruneau; Vivien Béziat; Bertrand Boisson; Lazaro Lorenzo-Diaz; Soraya Boucherit; Mylène Sebagh; Emmanuel Jacquemin; Jean-François Emile; Laurent Abel; Charles M. Rice; Emmanuelle Jouanguy; Jean-Laurent Casanova
DOI: 10.1084/jem.20190669
Article
Jérémie Decalf; Sandrine Fernandes; Randy Longman; Mina Ahloulay; Françoise Audat; François Lefrerre; Charles M. Rice; Stanislas Pol; Matthew L. Albert
DOI: 10.1084/jem.20070814
Brief Definitive Report
Giovanna Barba-Spaeth; Randy S. Longman; Matthew L. Albert; Charles M. Rice
DOI: 10.1084/jem.20051352
Article
Deng Tao; Giovanna Barba-Spaeth; Urvashi Rai; Victor Nussenzweig; Charles M. Rice; Ruth S. Nussenzweig
DOI: 10.1084/jem.20041526
Article
Naglaa H. Shoukry; Arash Grakoui; Michael Houghton; David Y. Chien; John Ghrayeb; Keith A. Reimann; Christopher M. Walker
DOI: 10.1084/jem.20030239
Article
M A Minutello; P Pileri; D Unutmaz; S Censini; G Kuo; M Houghton; M R Brunetto; F Bonino; S Abrignani
DOI: 10.1084/jem.178.1.17
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