Observations are reported on the changes which occurred in excised rabbit and human skin after mild trauma and incubation at body temperature. These changes resembled those of chronic inflammation, in that perivascular and diffuse infiltration by histiocytes occurred in the corium and subcutaneous tissue, but they developed within a few hours. The experiments have shown that even after removal from the body certain tissue elements may retain the ability to react with proliferative changes in response to tissue injury if kept under artificially simulated physiological conditions. The possible significance of these changes in relation to the inflammatory process is discussed.
THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION
- Views Icon Views
- PDF LinkPDF
- Share Icon Share
- Search Site
Jean V. Cooke, David Goldring, Lawrence I. Kahn; THE OCCURRENCE OF CHANGES RESEMBLING THE INFLAMMATORY IN SKIN INJURED AND INCUBATED AFTER EXCISION . J Exp Med 1 May 1953; 97 (5): 651–662. doi: https://doi.org/10.1084/jem.97.5.651
Download citation file: