Young mice infected with Group B Coxsackie virus were rendered markedly resistant to poliomyelitis virus given from 4 to 10 days later. A sparing effect was detectable in somewhat older mice and in young mice inoculated with poliomyelitis after shorter intervals, but in both cases few mice survived.

Interference was manifest by survival, by prolongation of the course of poliomyelitis, and by a decreased frequency of poliomyelitis.

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