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Volume 84, Issue 4
1 October 1946
Journal of Experimental Medicine Cover Image for Volume 84, Issue 4
Article| October 01 1946

STUDIES ON THE MECHANISM OF RECOVERY IN PNEUMOCOCCAL PNEUMONIA : III. FACTORS INFLUENCING THE PHAGOCYTOSIS OF PNEUMOCOCCI IN THE LUNG DURING SULFONAMIDE THERAPY

W. Barry Wood, Jr.,
W. Barry Wood, Jr.
From the Department of Medicine, Washington University School of Medicine, and the Oscar Johnson Institute for Medical Research, St. Louis, and the Departmert of Medicine, Johns Hopkins University School of Medicine, Baltimore
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Charlotte McLeod,
Charlotte McLeod
From the Department of Medicine, Washington University School of Medicine, and the Oscar Johnson Institute for Medical Research, St. Louis, and the Departmert of Medicine, Johns Hopkins University School of Medicine, Baltimore
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Edwin N. Irons
Edwin N. Irons
From the Department of Medicine, Washington University School of Medicine, and the Oscar Johnson Institute for Medical Research, St. Louis, and the Departmert of Medicine, Johns Hopkins University School of Medicine, Baltimore
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Author and Article Information
W. Barry Wood, Jr.
From the Department of Medicine, Washington University School of Medicine, and the Oscar Johnson Institute for Medical Research, St. Louis, and the Departmert of Medicine, Johns Hopkins University School of Medicine, Baltimore
Charlotte McLeod
From the Department of Medicine, Washington University School of Medicine, and the Oscar Johnson Institute for Medical Research, St. Louis, and the Departmert of Medicine, Johns Hopkins University School of Medicine, Baltimore
Edwin N. Irons
From the Department of Medicine, Washington University School of Medicine, and the Oscar Johnson Institute for Medical Research, St. Louis, and the Departmert of Medicine, Johns Hopkins University School of Medicine, Baltimore
Received: June 09 1946
Online ISSN: 1540-9538
Print ISSN: 0022-1007
Copyright, 1946, by The Rockefeller Institute for Medical Research New York
1946
J Exp Med (1946) 84 (4): 377–386.
https://doi.org/10.1084/jem.84.4.377
Article history
Received:
June 09 1946

The phagocytosis which occurs in the lungs of rats receiving sulfonamide is due neither to an opsonizing action of the sulfonamides nor to type-specific antibody. The evidence presented indicates that the destruction of the pneumococci is brought about by a phagocytic mechanism independent of both opsonization and capsular injury.

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Copyright, 1946, by The Rockefeller Institute for Medical Research New York
1946
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