HEREDITY OF THE Rh BLOOD TYPES II. OBSERVATIONS ON THE RELATION OF FACTOR HR TO THE RH BLOOD TYPES

Wiener , Alexander S.; Davidsohn , I.; Potter , E. L.

doi:10.1084/jem.81.1.63

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Article| January 01 1945

HEREDITY OF THE Rh BLOOD TYPES : II. OBSERVATIONS ON THE RELATION OF FACTOR HR TO THE RH BLOOD TYPES

Alexander S. Wiener,

Alexander S. Wiener

From the Office of the Chief Medical Examiner of the City of New York, the Mount Sinai Hospital of Chicago, and the Department of Obstetrics and Gynecology of The University of Chicago

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I. Davidsohn,

I. Davidsohn

From the Office of the Chief Medical Examiner of the City of New York, the Mount Sinai Hospital of Chicago, and the Department of Obstetrics and Gynecology of The University of Chicago

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E. L. Potter

From the Office of the Chief Medical Examiner of the City of New York, the Mount Sinai Hospital of Chicago, and the Department of Obstetrics and Gynecology of The University of Chicago

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Author and Article Information

Alexander S. Wiener

From the Office of the Chief Medical Examiner of the City of New York, the Mount Sinai Hospital of Chicago, and the Department of Obstetrics and Gynecology of The University of Chicago

I. Davidsohn

From the Office of the Chief Medical Examiner of the City of New York, the Mount Sinai Hospital of Chicago, and the Department of Obstetrics and Gynecology of The University of Chicago

E. L. Potter

From the Office of the Chief Medical Examiner of the City of New York, the Mount Sinai Hospital of Chicago, and the Department of Obstetrics and Gynecology of The University of Chicago

Received: September 21 1944

Online ISSN: 1540-9538

Print ISSN: 0022-1007

Copyright, 1945, by The Rockefeller Institute for Medical Research New York

1945

J Exp Med (1945) 81 (1): 63–72.

https://doi.org/10.1084/jem.81.1.63

1. The theory of six allelic genes is reviewed, using the new improved nomenclature, and data are summarized regarding the distributions of the eight Rh types among white and negro individuals in New York City.

2. Results are presented of tests for property Hr in a series of 239 white individuals and 49 negroes. Statistical analysis of these data yields results supporting Race and Taylor's hypothesis that anti-Hr sera react with the blood properties determined by the genes Rh₂, Rh'' Rh_o, and rh, but not with the factors determined by genes Rh₁ and Rh'.

3. The practical importance of the Hr factor is discussed.

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Copyright, 1945, by The Rockefeller Institute for Medical Research New York

1945

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