Rabbits sensitized to horse serum developed a bacteremia of 9 to 12 hours' duration when they were inoculated simultaneously with normal horse serum and a strain of Streptococcus hemolyticus, while the bacteria could only be isolated from the blood stream of non-sensitized animals within the first 3 hours after inoculation. On the other hand, when antisera are employed as the antigen for shocking the sensitized rabbits, there is a significant increase in the number of bacteria in the blood stream in contrast to the control animals, but there is no evidence of a prolongation of the bacteremia.
THE PRODUCTION OF STREPTOCOCCUS HEMOLYTICUS BACTEREMIA IN NON-SPECIFICALLY SENSITIZED ANIMALS
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Caspar G. Burn, Caroline A. Chandler, Mildred Hartshorn; THE PRODUCTION OF STREPTOCOCCUS HEMOLYTICUS BACTEREMIA IN NON-SPECIFICALLY SENSITIZED ANIMALS . J Exp Med 1 July 1934; 60 (1): 1–7. doi: https://doi.org/10.1084/jem.60.1.1
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