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Volume 53, Issue 4
1 April 1931
Journal of Experimental Medicine Cover Image for Volume 53, Issue 4
Article| April 01 1931

THE ETIOLOGY OF ACUTE UPPER RESPIRATORY INFECTION (COMMON COLD)

Perrin H. Long,
Perrin H. Long
From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore
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James A. Doull,
James A. Doull
From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore
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Janet M. Bourn,
Janet M. Bourn
From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore
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Emily McComb
Emily McComb
From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore
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Author and Article Information
Perrin H. Long
From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore
James A. Doull
From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore
Janet M. Bourn
From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore
Emily McComb
From the Department of Medicine and the Clinical Laboratory of the John J. Abel Fund for Research on the Common Cold, The Johns Hopkins University, Baltimore
Received: December 28 1930
Online ISSN: 1540-9538
Print ISSN: 0022-1007
Copyright, 1931, by The Rockefeller Institute for Medical Research New York
1931
J Exp Med (1931) 53 (4): 447–470.
https://doi.org/10.1084/jem.53.4.447
Article history
Received:
December 28 1930

Experimental upper respiratory infections similar to "common colds" were transmitted singly and in series through two and four passages in nine out of fifteen persons, by intransal inoculations with bacteria-free filtrates of nasopharyngeal washings obtained from individuals ill with natural "colds." These observations conform with those reported by previous workers and lend further support to the view that the incitant of the "common cold" is a filtrable virus.

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Copyright, 1931, by The Rockefeller Institute for Medical Research New York
1931
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