Ground muscle from susceptible chickens fixes in vitro in a proportion of instances the agent of the filterable Chicken Tumor I, and in a lesser degree inactivates it, whereas the muscle from resistant animals such as rabbit and pigeon, is without effect. It is shown that the power of fixation of the chicken muscle is far greater than its inactivating properties.

Brain and liver from chicken, rabbit and pigeon seem devoid of any action on the agent.

The desiccated chicken muscle tissue shares the properties of the fresh organ; and the process of desiccation does not release the agent from the inactive or slightly active mixture of fresh muscle and filtrate.

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