A non-protein gum has been isolated from broth filtrates of human tubercle bacilli grown on a simple medium. It fixes complement and precipitates in high dilution in the presence of homologous immune serum, but fails to give a skin test in tuberculous animals. The preparation and some of the chemical properties of the substance are described.
Article| January 01 1926
A CHEMICAL STUDY OF THE SPECIFIC ELEMENTS OF TUBERCULIN : II. THE PREPARATION OF RESIDUE ANTIGEN FROM OLD TUBERCULIN.
J. Howard Mueller
From the Department of Bacteriology and Immunology, Harvard University Medical School, Boston.
Received: September 20 1925
Online Issn: 1540-9538
Print Issn: 0022-1007
Copyright, 1926, by The Rockefeller Institute for Medical Research New York
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J. Howard Mueller; A CHEMICAL STUDY OF THE SPECIFIC ELEMENTS OF TUBERCULIN : II. THE PREPARATION OF RESIDUE ANTIGEN FROM OLD TUBERCULIN. . J Exp Med 1 January 1926; 43 (1): 9–12. doi: https://doi.org/10.1084/jem.43.1.9
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