THE RELATION OF DOSE OF BACTERIA TO GROUP INFECTION

Bloomfield , Arthur L.; Felty , Augustus R.

doi:10.1084/jem.40.5.679

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Article| November 01 1924

THE RELATION OF DOSE OF BACTERIA TO GROUP INFECTION

Arthur L. Bloomfield,

Arthur L. Bloomfield

From the Biological Division of the Medical Clinic of the Johns Hopkins University and Hospital, Baltimore.

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Augustus R. Felty

From the Biological Division of the Medical Clinic of the Johns Hopkins University and Hospital, Baltimore.

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Author and Article Information

Arthur L. Bloomfield

From the Biological Division of the Medical Clinic of the Johns Hopkins University and Hospital, Baltimore.

Augustus R. Felty

From the Biological Division of the Medical Clinic of the Johns Hopkins University and Hospital, Baltimore.

Received: June 25 1924

Online ISSN: 1540-9538

Print ISSN: 0022-1007

Copyright, 1924, by The Rockefeller Institute for Medical Research New York

1924

J Exp Med (1924) 40 (5): 679–701.

https://doi.org/10.1084/jem.40.5.679

A study has been made of the peritoneal reaction in mice after injection of different bacteria in graded dose. Organisms were employed to which the animals were fairly resistant. Under these conditions it was found that as the dosage was decreased a more or less critical point was reached below which infection failed to be initiated.

The possible clinical bearings of this observation are discussed.

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Copyright, 1924, by The Rockefeller Institute for Medical Research New York

1924

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