1. The resistance of rats to bacterial intoxication is greatly decreased after double adrenalectomy.

2. This decreased resistance is dependent upon a functional insufficiency of the adrenal cortex.

3. A dose of killed streptococci or staphylococci can be obtained that is invariably fatal to adrenalectomized rats, before hypertrophy of cortical accessories, but never kills control rats.

This content is only available as a PDF.