The meningococcus, like some other pathogenic species, varies in its agglutination in immune serum, some strains being readily agglutinable while others agglutinate with difficulty in their homologous serum as well as in heterologous serums. The different strains appear to vary also in their action as antigens. In order to secure representative strains, therefore, it was thought necessary to consider the antigenic action as well as the agglutinability of the cultures.

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