Exposure of rabbits to an atmosphere of low oxygen content results in a stimulation of the cardiorespiratory systems, in an extension (hyperplasia) of red bone marrow and probably of a thyroid hyperplasia, with the further production of hydropic and hyaline degeneration in the cells of the parenchymatous organs. An atmosphere of high carbon dioxide and normal oxygen content produces, however, a stimulation of the cardiorespiratory systems, but no marrow extension and, in the concentrations used, but slight hydropic degeneration in the parenchyma of the glandular organs.

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